from what i've read the exact mechanisms behind it are not fully understood yet. (i hadn't even heard the term anaphylactoid reaction before looking into this.)
The main difference, in this link of an anaphylactic risk with NAC is the route of administration.
I have to take 2 Epipens with me, due to a life-threatening anaphylactic reaction to bee stings. But never from oral 700 mg NAC doses.
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