Myalgic Encephalomyelitis is clear to see in the blood

[Dysfunkion]

I agree with the general gist of what you say. This is the thing. Say in autism, or heart disease, we see different expressions of illnesses. Breast cancer is the same. I think it's nine distinct illnesses.
But the fact that wishful wants to ignore vast swathes if evidence is plain ignorant

So if I read that right what you're saying is you think there is nine different core illnesses at the heart of various conditions and that the conditions overlaying them can overlap and this is part of what creates the phenotypes? I hope I understood that all correctly.

 

[NameHere]

• Specific probiotics (e.g., Lactobacillus plantarum, Bifidobacterium longum, Akkermansia)
• Sodium butyrate or tributyrin to restore SCFA production
• Glutamine, zinc carnosine, quercetin, vitamin D to repair mucosal barriers
• Antimicrobial herbal therapy (when specific pathogens are detected)
• Personalized elimination diets (low-FODMAP, gluten-free, histamine-free…)
• Antifungal treatments (if Candida spp. overgrowth is present)

I talk about this topic in more detail in this article:
https://fatigacronica.es/alteraciones-digestivas-sfc-em/

Excellent article. I would be interested to know if there have been any studies showing before/after zonulin, or before/after lactulose-mannitol test, proving that these things increase intestinal barrier function. So far, I haven't found anything in my pubmed searches.

 

[Oliver3]

So if I read that right what you're saying is you think there is nine different core illnesses at the heart of various conditions and that the conditions overlaying them can overlap and this is part of what creates the phenotypes? I hope I understood that all correctly.

https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1305972/full

I'm not saying it's 9 different illnesses. That's specific to breast cancer I believe but yes the same idea applies. The phenotypes in m.e. seem remarkably similar to conditions such as fibro., comorbid with autisn etc..like you say, depending how genes and epigenetics are expressed, these genes are expressed in certain ways to fit into certain phenotypes.

The rcccx theory covers this idea and I think it's correct. Ibs, migraine, intercranial hypertension. Brain profusion.. ut depends what and how these genes that are expressed that creates the phenotype such as tge or I posted I'm the study

 

[Oliver3]

I am NOT trying to be a Negative Nelly, but this was my takeaway from the original linked reference:



Am I missing something? (Please be gentle in your response, thank you.)

It's a very generic biomarker but it points to a system understress