bertiedog
Senior Member
- Messages
- 1,745
- Location
- South East England, UK
I have done really well energy-wise with 5000 mcg Transdermal B12 spray which I think contains Cynacobalamin as well as 400 mcg Folapro. The sustained energy has been the best I have had since 2000 when I finally crashed with ME/CFS. I have however had difficulties with severe migraines which were almost unbearable when I added 1000 mcg MB12 lozenge. I kept to my normal other supplements which include Thornes Basic NutrientsIII which includes more MB12, AdnB12, methylfolate and calcium folinate but only in lowish doses.
The other problem I experienced was quite severe overstimulation especially when the MB12 was added. Within 3 days of taking this I could hardly sleep at night and was lucky to get 4 hours even with taking some clonazapan which I don't normally need at all.
The migraines became so severe my life didn't seem worth living which I know sounds very dramatic but the pain and the way I felt meant I could obviously no longer continue in this way. No way could I do what Fredd says and soldier on.
Since Sunday this week I dropped the TDB12 spray to 2000 mcg and didn't take any extra folates of MB12. Within 2 days my energy had dropped considerably and within 4 days I had lost all the ground I had made so I pushed the TD B12 spray back up to 5000 mcg and added back 400 mcg Folapro. The effect was immediate, great energy and mood just slight stimulation by mid afternoon and evening and only 5 1/2 hours sleep.
So today I had good energy on waking, used the TD B12 spray at 4000 mcg and took 800 Folapro. Within 4 hours of this I started to develop a slight pain in my head which has gone on building to a migraine. My mood is much lower and so is my energy.
So it is obvious I need at least 400 mcg methylfolate to go with the 200 mcg that is in the BN (plus 200 calcium folinate) whereas I don't appear to need extra MB12 at this stage, I respond really well to 5000 mcg TD B12 spray. I wonder if it is possible that I should only take a dose of methylfolate every other day to avoid the migraines? Is there anything obvious that I am missing?
I continue with stuff like fish oil Vitamin E, starflower oil, zinc, Vitamin D, Q10 etc and I eat an excellent good protein diet with low carbs. However on a recent blood test and previously my level of protein in the blood is below the range so I do need to take digestive enzymes with some betaine.
It is so difficult to get the balance right. I have been taking supplements for methylation since 2007 but always experience the migraines with MB12 and methylfolate but not the TD spray.
Pam
The other problem I experienced was quite severe overstimulation especially when the MB12 was added. Within 3 days of taking this I could hardly sleep at night and was lucky to get 4 hours even with taking some clonazapan which I don't normally need at all.
The migraines became so severe my life didn't seem worth living which I know sounds very dramatic but the pain and the way I felt meant I could obviously no longer continue in this way. No way could I do what Fredd says and soldier on.
Since Sunday this week I dropped the TDB12 spray to 2000 mcg and didn't take any extra folates of MB12. Within 2 days my energy had dropped considerably and within 4 days I had lost all the ground I had made so I pushed the TD B12 spray back up to 5000 mcg and added back 400 mcg Folapro. The effect was immediate, great energy and mood just slight stimulation by mid afternoon and evening and only 5 1/2 hours sleep.
So today I had good energy on waking, used the TD B12 spray at 4000 mcg and took 800 Folapro. Within 4 hours of this I started to develop a slight pain in my head which has gone on building to a migraine. My mood is much lower and so is my energy.
So it is obvious I need at least 400 mcg methylfolate to go with the 200 mcg that is in the BN (plus 200 calcium folinate) whereas I don't appear to need extra MB12 at this stage, I respond really well to 5000 mcg TD B12 spray. I wonder if it is possible that I should only take a dose of methylfolate every other day to avoid the migraines? Is there anything obvious that I am missing?
I continue with stuff like fish oil Vitamin E, starflower oil, zinc, Vitamin D, Q10 etc and I eat an excellent good protein diet with low carbs. However on a recent blood test and previously my level of protein in the blood is below the range so I do need to take digestive enzymes with some betaine.
It is so difficult to get the balance right. I have been taking supplements for methylation since 2007 but always experience the migraines with MB12 and methylfolate but not the TD spray.
Pam