- Messages
- 48
- Location
- Montague, MA
how to assess what kind of B12 will be best for me
I have an immediate, mildly unpleasant response to the Hydroxy B12. I accidently ordered the sublingual lozenge rather than the drops from Holistic Health. So i am wondering if it might be the fillers or the sorbitol. So I could try the drops or another brand HydroxyB12. I am concerned about cost. I get my supplements wholesale as I am a healthcare provider and wonder if I might use one of the Hydroxy B12's offered there. They are high quality brands often only sold through doctors offices. I don't understand why the drops from Holistic Health are so expensive. My doctor's office sells one called Perque Guard activated B12 which is Hydroxy form. Anyone have experience with that? That is available through my wholesale distributor. There are many other brands as well. r
I wish I knew how to reply the way you do Rich. want to give a little on-line lesson? I tried replying with include quote but it did not allow me to preview it saying I had too few characters. (?)
Hi, Lucy.
It is difficult to sort out whether there is a reaction to the supplements or whether the detox system is mobilizing toxins because it has started to function better as a result of the supplements. I am currently suggesting that people stick with the SMP for three months before deciding whether it's helping or not. If it doesn't seem to be producing positive results by three months, then I think something needs to be changed.
When you had the trial on methyl B12 injections, were you also supplementing active folate, such as methylfolate? If not, this may be the reason you did not experience a response. It's necessary to supplement B12 and folate together to lift the partial methylation cycle block. From what you've reported, it does seem that you receive a positive response to methylfolate.
No I was not.
The easiest thing to do to try to determine which B12 is best for you is to try one for 3 months, and if it isn't helping, try the other.
If you are planning to run a urine organic acids test, I would recommend the Genova Diagnostics Metabolic Analysis Profile, because it has both Figlu and MMA on it. It will give indirect information about the status of your methylation cycle, folate metabolism, and glutathione. However, it will not tell you which B12 form would be best.
Dr. Amy Yasko offers a nutrigenomic panel, and from the results for the COMT and VDR Bsm SNPs, she determines whether hydroxo B12 or methyl B12 is better for the person. I don't know of published experimental support for this approach. She bases it on her experience.
Best regards,
Rich
I have an immediate, mildly unpleasant response to the Hydroxy B12. I accidently ordered the sublingual lozenge rather than the drops from Holistic Health. So i am wondering if it might be the fillers or the sorbitol. So I could try the drops or another brand HydroxyB12. I am concerned about cost. I get my supplements wholesale as I am a healthcare provider and wonder if I might use one of the Hydroxy B12's offered there. They are high quality brands often only sold through doctors offices. I don't understand why the drops from Holistic Health are so expensive. My doctor's office sells one called Perque Guard activated B12 which is Hydroxy form. Anyone have experience with that? That is available through my wholesale distributor. There are many other brands as well. r
I wish I knew how to reply the way you do Rich. want to give a little on-line lesson? I tried replying with include quote but it did not allow me to preview it saying I had too few characters. (?)