Did you change anything? Add anything, eliminate anything? Yes. A gradual increase of MB12, adding in trials of AB12, methylcobalamin (200 mcg), and potassium (under 300 mcg).
What brand of MeCbl?
Two brands: mostly Kirkland 5,000 mcg and (brief trial of) Jarrow 5,000 mcg.
Did you increase B1, B2 or B3?
No. Taking Seeking Health chewable multivitamin only, on and off.
Let's think about what could be causing this. I have to have 30mg/day injected SC in 3 doses or I have that happening.
Do you have foot drop?
No.
What about vibration test properly done?
Diminished vibration in test two days ago but no worse than worst position before starting MB12.
Balance? Awareness of position?
Abnormal gait, balance, tandem walk all improved after 30+ days (or so) on MB12. With this recurrence of numbness/stiffness, gait (balance) slightly worse than best on MB12. However, mental state still optimal--much better than before MB12 and has apparently not declined.
Is the skin numb?
Yes, slight in upper leg/hands/lower arms, moderate in lower legs, more severe in feet particularly soles. Thumbs, first two fingers stiffening, more difficult to articulate.
Are muscles, such as in the feet, numb? Both in same places or different places?
I do not think so although I do have stiffness. Numbness seems to be surface/near surface because where touch cannot be felt, pressure can be.
Do you think it is centrally caused or peripheral or something like a bulging disk?
Radiculopathy a possibility but not likely. Condition is highly symmetric, involving both lower and upper body notwithstanding long-held dermatomes. See my conjecture below.
Did it take sudden discrete jumps or sort of a smooth steady change?
Smooth, steady.
Were there a variety of paresthesias as they got worse?
Negligible, minor muscle contractions, minor twitches.
Based on putting together multiple sources of n=1 published case histories and an n= thirty something on cyanide exposure and reversal by HyCbl, and personal experience, it takes about 2 weeks post methyltrap initiation to cause/increase CNS (brain/cord) demyelination.
Do you use bismuth in any way, say as Pepto?
No.