Methylation Journal-Misfit Toy

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88
Location
NJ
@Misfit Toy - I know you know how bad sugar is for the body, especially people with compromised health, as we all are here. l-glutamine may be able to help with your cravings - see http://healthdivas.blogspot.com/2012/09/shortcut-to-stop-sugar-and-starch.html

You mentioned adrenal problems and anxiety, and again, these are exacerbated by sugar. My sister has rheumatoid arthritis and is also a self-described sugar addict, but eating sugar is like playing with fire for her. She'd get off it, go back on it, over and over, until her husband told her to think of sugar as being like heroin for her. And that finally got through to her, and she quit it (along with white flour etc.)

Also, do you know your lithium levels? low lithium can cause anxiety. I take 5 mg. of Swanson's brand lithium orotate.

Good luck!

My glutamine was sky high and I still got sugar cravings.
 

Mary

Moderator Resource
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18,313
Location
Texas Hill Country
My glutamine was sky high and I still got sugar cravings.

Wow - well, that's too bad I guess. It didn't help Misfit Toy either. FWIW, I think it did affect my blood sugar in a positive way. I wouldn't say I generally have sugar cravings - I keep a pretty steady level, eating protein snacks as needed and I almost never eat sugar anyways. I tend to have salt cravings. However, I did notice after starting the glutamine that I could go longer without eating.

But we're all so different!
 

Critterina

Senior Member
Messages
1,238
Location
Arizona, USA
I take my methyl B12 when I get up in the morning, too, with my thyroid and DHEA. I'd say "on an empty stomach" but I take sublingual. No problems as far as I can tell, and in fact the opposite - seems to be good thing.

@Misfit Toy , what are your dose increase plans? Did the liquid come in the mail?
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
@Critterina -yes, it did! The liquid came in the mail and I took it. I felt nothing, but it also is tasteless, which may mean nothing!! Last night, I put a little bit of B12 under my tongue (the pill) and instead of it revving me up, I fell asleep...I slept great. I think right now I am at 250 mcg, so I jumped up by double and I am having no problems.

I am taking the yucca, too and increased that also.

My mom told me today that when she was little she had to be on B12 due to bloodwork, but she didn't know why...she is almost 86 and doesn't remember much. I think it's interesting because she has been so tired lately and she said she take B12 everyday and she is upping it from 1,000 mcg to 2,000 mcg.

Critter, I will PM you later! I have been busy.

I am having a better past couple of days due to God knows what. I was able to get out, go swimming and I took my mom for a ride last night. It's been a nice reprieve which I wish would last!
 

Misfit Toy

Senior Member
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4,178
Location
USA
I am very happy that I haven't had any negative side effects from the B12, now being at 250 mcg of Hydroxy. Nor, the Yucca or the Moly. I have been sleeping pretty okay.

I never know why though. It may have nothing to do with the supplements but it could be the stars are aligned for sleeping for whatever reason. I will take it.

I am feeling a bit down. It's the time of my menstrual cycle and I am quite upset about the MCAS and intolerances of so many things. So many things that people can take, I can't. The Valcyte, LDN, all of these things make me so sick, or with LDN sleep deprived.

When I try new things, I have to have zero planned because these things will cause a crash that takes days to weeks to get out of. The last medicine I tried for Sjogrens was enbrel which caused serum sickness. I was SO sick and had to go on prednisone and benadryl around the clock.

I wanted to kill myself which led me to seek out help from a psychiatrist. The prednisone did me in. Once off of it I was better showing that the pred did it, but what's interesting is that there are times I am okay on Prednisone and other times, not at all.

So, I read all of the treatments on here for this illness and I wonder how so many people can do and see these specialists, leave with a boatload of prescriptions and take them. I would be sicker than a dog. With all of our sensitivities, it baffles me but we are all different with a different kind of illness.

I sat outside a couple of times last week and bugs must have bitten me and I have welts all over, which is proof that I can not experiment right now with drugs. I didn't have mosquitoes biting me, but little gnat like bugs and I have itchy welts. All over. I have never had this....ever. This shows me how reactive my system is because I try to sit out every year in the summer, because the sun is so good for me. I have never had a reaction to bug bites like this.

My body is a mess.

I am so grateful for being able to tolerate the B12, thus far but also know this is not a cure and none of this might even work. Some do well on methylation, some see no benefit at all, or get worse. And some get locked in a maze where they are tinkering around with so many minerals, etc...

I am truly hoping I don't go down that route, but at the pace I am going...slow, it's all good for now.
 
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Misfit Toy

Senior Member
Messages
4,178
Location
USA
I'm up to 1,000 mcg of hydroxyB-12. I don't feel jittery, etc. I've noticed a better mood, but not sure if that's it. Still on Yucca and Moly.

Here's hoping for some improvement that lasts!

I am wondering if I need the adeno b12?
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
I have had a major setback and I am not taking anything today. I went from 125 mcg of B12 to 1,000 mcg of B12 in 2 weeks. I suppose my rationale was that I wasn't having any problems and I wasn't feeling hyped.

I also upped the Yucca for sulfur and ammonia and was taking the Moly. I am not on Folate. I tried lithium orotate last night and became sleepy and anxious and I was hyperventilating.

Over the past few days I have noticed an obsessiveness and just feeling unhinged and detached. A depression.

It's very hard to separate what is doing what as I have other things going on but in the middle of the night, I just knew...I am pushing with this. With the B12 and the Yucca.

It comes down to being tired of being sick and wanting to get better now. I want to brain fog and the lack of energy to lift.

Not doing too well and my spirit is down. I feel like things from the past...what happened years ago has resurfaced in my head and have come back to hit me in the face. Years ago....I am living in the past and dealing with past hurts.

@caledonia @Critterina
 
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AndyPandy

Making the most of it
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1,928
Location
Australia
Sorry that you are not doing too well. I am no expert, but perhaps you have increased doses of B12 and other things too quickly?

Also too many things at the same time?

I am very sensitive too and am still on the same dose after 8 weeks. I felt that if I increased by too much or too quickly I would end up very agitated and possibly in a whole lot of trouble with other reactions.

I am also taking B2 which I have been told helps with reactions. I have a number of MAO +/+ snps which I have been told makes B2 more important. Do you have any of these?

It would be great if you could find a practitioner to give you individualised guidance on this.

It is so hard to take things slowly when we just want to get better right now.

Dealing with the past is so tough. I hope you are still getting some help with that.

Thinking of you.

BTW I also get big swellings from insect bites.
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
@AndyPandy -thank you for responding. I still haven't learned everything regarding my tests meaning haven't studied it enough to know much about it yet. I've been pretty sick for about five days.

I do think that raising the dosage of everything was not such a good idea, but I'm not so sure that's the only culprit here. It's so hard to know. Im so glad you have someone to speak with about this feel, I feel like I'm in the dark. I don't know how to go about it. Not knowing how to go about it -I will not continue. I don't have the mental capability of learning everything.

The bug bites situation is really concerning because I've never had anything like this before. Strange!

I'm going to go back down on the B12 and other things. Today I took a total break from it all. Spent my day in bed.

As far as getting help for the emotional stuff – the problem is is that there's only so much talking you can do. What I really need his medication, but like everything else I'm reacting to medicines. All of them.

Thank you for responding. I'm glad someone did.
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
I cut back on the b12 in a big way, but I'm still on the molybdenum and yucca. Something very strange is going on.

I feel like my mind is constantly in the past. Like I'm reliving it. I'm thinking of old flames, friends from years ago. I'm dreaming about them.

This brings on a sort of depression. I don't want to relive the past, I want to be in the here and now. I'm pretty positive it's the supplements because I'm not doing anything else new.
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
Another update. After feeling somewhat crazy for about 10 days, having increased inflammation and living in a past year..meaning, I feel like I am back in time...I started thinking about Molybdenum and Yucca and B12 and just how so many don't agree on several things with this whole methylation maze.

When I stood on the scale yesterday at my rheumatologist and realized wow...I have lost 10 pounds in a few months. And..I had to get a cortisone shot and lidocaine shot due to inflammation that has me sacked and homebound...I thought...you know, this protocol is not working.

I have been worried about what I put in my mouth due to sulfur issues, ammonia issues, I have become even more obsessed with food. This is BS. I am sicker. Don't eat chicken, don't eat beef...don't eat eggs, don't eat this or that...don't eat broccoli...

NO. Enough.

I don't want to be anorexic and scared of food. Isn't it enough to not be able to drink milk, have celiac, not be able to tolerate tomatoes, soy...etc? What am I eating? I am bored with food. I don't want to eat anymore. I have become nuts about food.

I reached out to Caledonia and she responded that Moly can cause you to dump too much copper. Well, that's huge because copper makes you nuts. Especially around the time of one's menstrual cycle. I read an article days ago about copper and how it causes MCAS...interesting since I have suddenly developed that.

I am speaking with a nutritionist tonight who deals with functional medicine. She doesn't feel that 23 and ME is enough..it's not enough to go by. You need blood work and urine analysis. You need the whole picture and food needs to be tailored by that.

She also feels that folate can be a living nightmare. Which we have seen on here.

There are so many theories...I have no idea what I am doing, but I am stopping the Molybdenum tonight.

AND...I AM EATING CHICKEN AND BROCCOLI.
 

Misfit Toy

Senior Member
Messages
4,178
Location
USA
@AndyPandy -it's awful. A few weeks ago I was at a friends house, I was busier and now I am beyond sick. I can't get a grip. Even my rheumatologist said yesterday..."I am not putting you on any medicine..you are too sick." He did want to put me on DHEA for the hormones and inflammation but I have that on hold. I can't take one more thing making me sick.

Maybe this nutritonist/functional medicine doc can help and if not...i am done with methylation. One mineral affects too many others and I can't afford to go nuts or get sicker. That's why I think this thing is so hard...we need a lab in our back yard to see just where we are all of the time...what is doing what to what.

Here's hoping I have an appetite sometime soon. I want to want to eat.

Andy....XXX
 

Snookum96

Senior Member
Messages
290
Location
Ontario, Canada
I just read through this journal and I must say you are such a strong and knowledgeable woman! I can't even understand half of the posts!

Good luck to you, I hope you find something that gives you some sustained improvement!
 
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