This is the thing, it's not clear what "leaky gut" is caused by...My point is, I wouldn't waste my time and effort on any leaky gut routine.
Same here. Leaky gut is often but not inevitably associated with ME (I've only been symptomatic for the last 12 years, but I've had ME since the mid-1970s), and it certainly isn't unique to ME. It's so widespread, and there are so many confounding factors for those trying to study it, that it could be a long while before it's fully understood.
I know I have a couple of severe food intolerances, and they're all I focus on nowadays – nothing else has ever really made a difference. It doesn't get any worse during ME relapses or remit during better phases, it just seems to be a condition that runs in parallel. Other women in my family also developed it after menopause, so I think it may just be another one of the joys of ageing for us!