- Messages
- 7
Hi all,
I'm new to this forum, but not methylation. I'm very familiar with Fredd and Rich's work, and am actually posting in the hopes of hearing from Freddd, especially because his of our shared potassium issues.
I tried to start methylation back in March of this year. I have CFS, histadelia, autoimmune diseases, MCS, IBS, etc. After about 5mcg B12, my potassium dropped so rapidly that within six hours I was unable to focus my vision, had severe tachycardia, I passed out and woke up paralyzed. Thanks to Freddd I was aware that potassium could be an issue, however I had no idea it would hit me so hard, so quickly. I passed out with my bottle of potassium and popped a handful every time I woke up, slowly regaining my strength.
I tried B12 a second time, but this time I went into the ER so I could catch it in blood work. My potassium has gone from 4.3 (after supplementing with horse pills) to 3.6 within about two hours. They wanted to discharge me but I begged them to retest me in another two hours. They agreed and my potassium had fallen again to something like 3.2. I was admitted and monitored but they wouldn't accept the fact that it was B12 causing this.
Anyway, after some near death experiences caused by histamines and adrenal insufficiency, I obviously had to put methylation on the back burner. I just recently started it again.
I began with 1mcg B12 and doubled this daily until around 60mcg methylcobalamin/day. At this point, inflammation and histamined were sky high. As per Freddd, this was likely a folate insufficiency. I took 50mcg Quatrefolic and felt much better.
I've taken 50mcg Quatrefolic (in the form of Jigsaw magnesium SRT which contains 2mcg methylcobalamin per 50mcg Quatrefolic) for a couple days. It seemed to help initially. I tried 50mcg methylfolate:15mcg methylcobalamin today and it's inflammation/histadelia central. Obviously, I can't do the B12. Or I need a lot more methylfolate:B12.
I do have MTHFR C677T, normal serum B12 (means nothing, I know) but also normal urine MMA. My histadelia has become unbearable since I started eating vegetables. Because of all this, I believe my biggest issue is a folate deficiency, which seems different to most people.
Freddd - if you're out there! What the heck do I do? Increase methylfolate slowly, while keeping an eye on potassium? I'm in a rough patch because nothing seems to be helping anymore. I've got high blood pressure headaches, joint paint, muscle weakness, muscle stiffness, extreme fatigue, puffy dry eyes - I get all these symptoms with high histamines just before anaphylaxis, and methylation breaks down histamines so I know there's a block. Have i created some donut hole with my tiny methylfolate doses? It seems like now that I've started, I can't just stop and go back, because the histamines don't stop rising anymore, so I have to keep supplementing but I'm not sure what the hell to take. I just know SAM-e is no longer helping, nor is B12. I am taking 50-70meq potassium daoily and so far my serum is looking good. (Trying to keep it ~4.1. It seems to drop ~0.4 in serum with each 50mcg folate dose.)
Would love to workshop this with someone who is on the outside looking in, and can see things more clearly.
Rachel
25 Years Old
CFS • MCS • Histadelia • IBS-C • Autoimmune • Secondary AI
I'm new to this forum, but not methylation. I'm very familiar with Fredd and Rich's work, and am actually posting in the hopes of hearing from Freddd, especially because his of our shared potassium issues.
I tried to start methylation back in March of this year. I have CFS, histadelia, autoimmune diseases, MCS, IBS, etc. After about 5mcg B12, my potassium dropped so rapidly that within six hours I was unable to focus my vision, had severe tachycardia, I passed out and woke up paralyzed. Thanks to Freddd I was aware that potassium could be an issue, however I had no idea it would hit me so hard, so quickly. I passed out with my bottle of potassium and popped a handful every time I woke up, slowly regaining my strength.
I tried B12 a second time, but this time I went into the ER so I could catch it in blood work. My potassium has gone from 4.3 (after supplementing with horse pills) to 3.6 within about two hours. They wanted to discharge me but I begged them to retest me in another two hours. They agreed and my potassium had fallen again to something like 3.2. I was admitted and monitored but they wouldn't accept the fact that it was B12 causing this.
Anyway, after some near death experiences caused by histamines and adrenal insufficiency, I obviously had to put methylation on the back burner. I just recently started it again.
I began with 1mcg B12 and doubled this daily until around 60mcg methylcobalamin/day. At this point, inflammation and histamined were sky high. As per Freddd, this was likely a folate insufficiency. I took 50mcg Quatrefolic and felt much better.
I've taken 50mcg Quatrefolic (in the form of Jigsaw magnesium SRT which contains 2mcg methylcobalamin per 50mcg Quatrefolic) for a couple days. It seemed to help initially. I tried 50mcg methylfolate:15mcg methylcobalamin today and it's inflammation/histadelia central. Obviously, I can't do the B12. Or I need a lot more methylfolate:B12.
I do have MTHFR C677T, normal serum B12 (means nothing, I know) but also normal urine MMA. My histadelia has become unbearable since I started eating vegetables. Because of all this, I believe my biggest issue is a folate deficiency, which seems different to most people.
Freddd - if you're out there! What the heck do I do? Increase methylfolate slowly, while keeping an eye on potassium? I'm in a rough patch because nothing seems to be helping anymore. I've got high blood pressure headaches, joint paint, muscle weakness, muscle stiffness, extreme fatigue, puffy dry eyes - I get all these symptoms with high histamines just before anaphylaxis, and methylation breaks down histamines so I know there's a block. Have i created some donut hole with my tiny methylfolate doses? It seems like now that I've started, I can't just stop and go back, because the histamines don't stop rising anymore, so I have to keep supplementing but I'm not sure what the hell to take. I just know SAM-e is no longer helping, nor is B12. I am taking 50-70meq potassium daoily and so far my serum is looking good. (Trying to keep it ~4.1. It seems to drop ~0.4 in serum with each 50mcg folate dose.)
Would love to workshop this with someone who is on the outside looking in, and can see things more clearly.
Rachel
25 Years Old
CFS • MCS • Histadelia • IBS-C • Autoimmune • Secondary AI