Ginger, I mean that RNA vaccine, as opposed to adjuvant vaccine, doesn't stimulate your full immune system, It just triggers a specific lymphocyte immune response to one foreign target protein. It was already shown that adjuvant vaccine stimulates immune activity in general and potential auto-immune response in susceptible individuals.
Thank you for explaining what you meant in your prior post
@pattismith. My doctor told me the same thing (that these COVID mRNA vaccines are safer than ANY vaccine with adjuvants for someone w/autoimmunity like me). The adjuvants cause the vaccines to speed up the immune response so it is even stronger (and more likely to trigger new autoimmunity or to worsen pre-existing autoimmunity).
However, it is not yet known what these mRNA vaccines will do to someone w/a history of severe autoimmunity (like me). Even though the Pfizer & Moderna vaccines do not contain traditional adjuvants, there are no studies (short or long-term) in how they affect autoimmunity. That is one of the main reasons that I will not be getting the vaccine when it is offered to me in the upcoming months.
If my autoimmunity was not in remission and I was still severely ill and disabled (like I was prior to treatment), than I actually probably would get the COVID vaccine b/c I would feel that I had nothing to lose. But being in remission from the autoimmunity, I feel that I have literally everything to lose if the vaccine ended my remission. I feel that I have a much great chance of damage from the vaccine than from COVID (for me personally).
So RNA vaccine seem less likely to trigger an auto-immune response unless the target protein is badly chosen and present some mimicry with a self antigen.
That is interesting re: the mimicry with a self-antigen.
Here a paper showing and adjuvanted vaccine in Sjogren patients can trigger an immune b lymphocyte response against EBV with increased EBV VCA IgG
I wanted to clarify (since I have minimal science background

), is this study with Sjogrens patients and vaccines an example of molecular mimicry (like you mentioned above) or is it simply showing how autoimmunity can be triggered by vaccines with adjuvants?
From my point of view, I cross fingers to be proposed a vaccine without adjuvant and with limited antigen content. RNA vaccine are typically the one I hope to get.
I agree w/you and if there was a scenario where I
had to get a COVID vaccine, I would absolutely want the one without adjuvants (Pfizer & Moderna). Can you explain more what you mean re: "limited antigen content"? Which of the existing COVID vaccines would fall into that category?
I got an adjuvanted flu vaccine last October, and it was a real nuclear weapon in my body. I am still inflamed in my enthesis, my brain and my skin and I can’t get another adjuvanted vaccine of any kind
I am so sorry to hear that and I have never gotten a flu vaccine in my life. When I had a neurotoxic reaction to a fluoroquinolone antibiotic in 2010 (which damaged the tendon in my arm and I ended up in hospital), I was told by a Neuro at that time that I should never get a flu vaccine in the future. Sadly, I did not learn of the specific reason why, but his words have stuck w/me. And now my current docs agree that I should never get a vaccine w/adjuvants, and ideally I should not get ANY vaccines. COVID is the one exception where they feel the risk could be worth it (and I totally understand why) but I am still not willing to risk ending my remission.