Someone, somewhere, on this forum, said that Lipkin's recruitment criteria (for Lipkin's XMRV study, and his sample bank) required the patients to have 'night sweats' to be included in the study.
I've just had a look at the paper, and it seems that this is a misunderstanding.
I think the misunderstanding comes from a description of ME which is included in the paper:
"Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME), is a disabling disorder characterized by persistent unexplained fatigue in association with impaired memory or cognition, muscle or joint pain, headache, sore throat, tender lymphadenopathy, and night sweats
I've just had a look at the recruitment criteria details, and they include the following:
Patients were required to have "reported a viral-like prodrome prior to the onset of CFS, defined as three or more
of the clinical features: fever, headache, gastrointestinal discomfort/upset, malaise, sore throat, myalgias, arthralgias, and tender lymph nodes"
So these symptoms were not
required to be present currently, but three or more
were required to be present prior
to onset of ME. (Night sweats were not
included in the recruitment criteria.)
There were also quite a number exclusion criteria, which included the following:
"Assays included screens for human immunodeficiency virus infection (HIV), syphilis (rapid plasmin reagin [RPR] test), hypothyroidism (T4 and thyroid-stimulating hormone [TSH] tests), hematocrit, white blood cell count, erythrocyte sedimentation rate, electrolytes, glucose, blood urea nitrogen, creatinine, and transaminases. Potential cases were excluded if screening laboratory values were not within the ranges shown in Table 1 or were HIV or RPR positive."
Table 1, is to be found here:
The 'white blood cell count' exclusionary criteria is relevent to Mark
's and rlc