Dreambirdie
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This is definitely of concern to me.
So it uses your methylation processes to replicate itself?
So, just to explain it again, here’s what it does:
What do others think? @Dufresne @AndyPandy @caledonia @Critterina @ahmo
http://ihateticks.me/2015/05/22/war...on-may-trigger-an-epstein-barr-virus-relapse/
So it uses your methylation processes to replicate itself?
So, just to explain it again, here’s what it does:
- EBV must first establish a latent B cell infection in order to keep them alive long enough to produce new viral particles
- EBV DNA is unmethylated upon infection, but becomes methylated over time by the host B cell
- The BZLF1-encoded protein, Zta (a cousin to AP-1), induces the viral lytic cycle (this means part of the reproductive cycle), but it prefers binding sites that are methylated. So the lytic phase gets delayed until enough methylation has occurred.
What do others think? @Dufresne @AndyPandy @caledonia @Critterina @ahmo
http://ihateticks.me/2015/05/22/war...on-may-trigger-an-epstein-barr-virus-relapse/