Personally, I find that Methylphenidate makes me very jittery and euphoric followed by a deep crash where I feel very depressed and anxious. If I combine caffeine with Methylphenidate, I feel even more miserable upon crashing.
Modafinil/Armodafinil use don't lead to any crash for me. They don't make me jittery nor euphoric and it's safe to combine them with caffeine without feeling jittery and nervous. They just offset the fatigue and brainfog "cleanly".
This seems like a very dangerous discussion. It's useful to consider out of the ordinary treatments, but one must consider risks involved,, with extreme caution for those with risk of permanent damage or death.
Heptaminol raises blood pressure, causes tachycardia and can trigger atrial fibrillation, which can cause strokes. Your next choice causes Parkinson's. Modanifil can cause mitochondrial damage.
It might be useful to look into the mechanisms which might be leading to the fatigue and solve those problems. They are finding COVID survivors have immune dysregulation, reactivated other viruses, and autoimmunity of different types.
Given that science leaders are noting the overlap between a certain portion of long COVID patients and those with ME/CFS, it might be interesting to look further into the mechanisms being found in the metabolomics studies. It might be worth looking into resources depleted by your illness, oxidative stress, mitochondrial repair and trying things that nurture your body and help it regain more normal function. Maybe antioxidants, mitochondrial nutrients, B vitamins, minerals, amino acids, and phospholipids....
It also might be less risky for some of the people reading this.
