Hyperthyroidism? severe insomnia

Learner1

Senior Member
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Pacific Northwest
@Mary You might find this helpful.

https://healthmatters.io/understand-blood-test-results/dopac

The NAC helping points to oxidative stress. Have you tried other antioxidants as well, like high dose melatonin (10-30mg), vitamins C & E, alpha lipoic acid, anthracyanins (the red/purple stuff in fruits)?

These are on glycine and taurine overload:
Screenshot_20221127-072534~2.png
Screenshot_20221127-072556~3.png

Could you be short of molybdenum?

Screenshot_20221127-072303.png

Does anything above stand out to you?

Have you looked into high ammonia, which ornithine or citrulline could help with and which could keep you up at night?

The other thing you might look at is your progesterone level. Deficient progesterone in women over 35 can definitely keep you up at night.
 

Mary

Moderator Resource
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17,094
Location
Southern California
Have you tried other antioxidants as well, like high dose melatonin (10-30mg), vitamins C & E, alpha lipoic acid, anthracyanins (the red/purple stuff in fruits)?
Hi @Learner1 - thanks for the suggestions - I've recently increased my melatonin to 9 mg (3 x 3 mg. caps), have been taking vitamin C and E and alpha lipoic acid for years and recently added in a pomegranate supplement.

Also, I take both taurine and glycine before bed which might account for the high levels. I recently stopped the taurine because it seemed to be contributing to my insomnia and now take it in the morning.

I have been taking ornithine - it didn't seem to make any difference. I don't think I have high ammonia at night. And citrulline unfortunately raises my blood pressure! It was supposed to the do the opposite.

I use a progesterone cream, and my levels are okay.

I still think my thyroid is involved. I just added in l-carnitine and went to sleep more quickly last night. l-carnitine is supposed to block T3 and T4 entry into the cell nuclei. Effects of carnitine on thyroid hormone action - PubMed (nih.gov) I first tried acelty-l-carnitine but that seemed to make the insomnia worse (!)

And I've been off my thyroid med for a few weeks now - I can't remember how long it's been - 3 weeks? (I'm out of town and don't have my notebook here) anyways, I've never gone this long without it without negative effects.

I've been taking 5 mg liquid doxepin at night for about 5 days - I don't like taking it, it leaves me woozy but I'm at my son's house and had to take something for sleep, I hope to stop it once I get home - if it has been my thyroid, hopefully it's calming down!