triffid113
Skimming for the gist
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I thought I'd share this article I just ran across at Life Extension. It basically says that people in general have more and more problems with hypercoagulablity of blood as they age and that inadequate blood flow causes pain. (This is what I understad to be true anyway - all pain is due to obstruction of blood flow and this oxygen to tissues). The culprit seems to be fibrin. That may not be the ultimate cause which may be viral but the lack of oxygen to tissues needs to be fixed, and can be fixed. (I know getting rid of a virus is the ultimate solution and continually getting rid of fibrin caused by a virus is well below optimal, but you gotta take care of what you can until you figure out he rest).
[My blood pressure went up this winter due to allergy caused thyroid problems (which also cause raised cholesterol and thus thickened blood). When spring came it did not go back to normal and I figured my arteries were clogged. I took 15mg K2 (MK-4) on alternate days with a natto pill and in 2 weeks I cleaned my arteries...of course they had not been clogged with years of clog. Natto is reputed to be important in clenaing up fibrin and MK-4 at cleaning up plaque...I think they work - you can investigate, but I just tried it and it seemed to do the trick for me. fyi, MK-7 canNOT be taken in such high dose as I have heard it is toxic in high dose. I am not an expert - that is just what I heard].
Here's the article: http://www.lef.org/magazine/mag2002...htm?source=search&key=blood viscosity testing
When tissues don't receive sufficient blood, the cells are starved for oxygen and nutrients. Pain can result, as in headache or fibromyalgia.
blah-blah-blah
When a trauma occurs, such as a severe infection, a car accident or severe emotional stress, most people eventually recover. But a minority go on to develop a chronic condition such as fibromyalgia. These individuals may be suffering from a genetic protein defect that makes them especially prone to develop hypercoagulability. High lipoprotein(a) also promotes hypercoagulability by blocking fibrinolysis. High homocysteine (over 10) is also associated with with hypercoagulability. High blood sugar and high triglycerides also promote elevated blood viscosity. Thromboxane, an eicosanoid derived through the metabolism of polyunsaturated fatty acids, is yet another factor promoting hypercoagulability. Altogether, the regulation of coagulation is quite complex, involving the balance of more than a dozen factors. It takes special tests to establish if a patient might be deficient in proteins C and S, for instance, or shows elevated fibrinogen.
Hypercoagulability can be easily detected through the use of the well-known "sed-rate" blood test. Sed rate of less than 5 indicates hypercoagulability. The difficulty comes in trying to find out the major factor(s) causing the condition. Thus the need for additional testing, so that the right factor (e.g., high lipoprotein(a) or high fibrinogen) can be targeted for treatment.
Virus infections have been singled out as particularly likely to provoke excess fibrin production. This fibrin accumulates in certain places, creating a "fibrin block" that impedes blood flow and deprives a certain area of the body of sufficient oxygen. Ryser said that she finds a history of two to six serious infections per every chronic fatigue patient. There is also suspicion that certain vaccines can act as precipitating agents for inflammation-induced hypercoagulability (e.g. anthrax vaccine contaminated with mycoplasma, a suspect in the Gulf War Syndrome).
...
Our understanding of the aging process is also enhanced by the perception that impeded blood flow leads to local ischemia (oxygen deficiency), and this is turn translates into progressive tissue atrophy. Only fifteen seconds of ischemia turns off the mitochondria. This initiates an apoptosis (programmed cell death) cascade. The shrinking of our organs with age leads to ever-greater pathology. Loss of heart tissue eventually results in congestive heart failure. Loss of glandular tissue results in hormone deficiencies, loss of neural tissue brings on cognitive dysfunction and eventually senile dementia, loss of lung tissue leads to emphysema, and so on. This is the atrophy of aging that we see throughout the body. The new insight is that "ischemia is a silent cause of aging and degenerative disease."
...
In order to fight ischemia, we need to keep the blood from getting too viscous and sluggish, and platelets from clumping too readily. We now see that various micronutrients are not only antioxidants, but also anticoagulants. Their great advantage is safety. We know how to counteract various procoagulant factors: high homocysteine, for instance, can be remedied through the use of folic acid, B12 and B6; aspirin, curcumin, ginger and ginkgo inhibit platelet aggregation; curcumin is also known to lower fibrinogen.
High lipoprotein(a) responds to niacin (or inositol hexanicotinate), high doses of vitamin C, and the amino acids lysine and proline. Hormone replacement and exercise also help maintain a more youthful blood circulation. Enzymes such as bromelain and Wobenzym have been found to lower blood viscosity. Even massage is seen in a new light when we learn that it helps release tissue plasminogen activator (tPA) from the lining of blood vessels, thus promoting better circulation.
...
they also mentioned heparin and glucosamine as anticoagulants.
---
I would choose natto tho'.
...
I don't know if anyone finds this helpful. Take care
[My blood pressure went up this winter due to allergy caused thyroid problems (which also cause raised cholesterol and thus thickened blood). When spring came it did not go back to normal and I figured my arteries were clogged. I took 15mg K2 (MK-4) on alternate days with a natto pill and in 2 weeks I cleaned my arteries...of course they had not been clogged with years of clog. Natto is reputed to be important in clenaing up fibrin and MK-4 at cleaning up plaque...I think they work - you can investigate, but I just tried it and it seemed to do the trick for me. fyi, MK-7 canNOT be taken in such high dose as I have heard it is toxic in high dose. I am not an expert - that is just what I heard].
Here's the article: http://www.lef.org/magazine/mag2002...htm?source=search&key=blood viscosity testing
When tissues don't receive sufficient blood, the cells are starved for oxygen and nutrients. Pain can result, as in headache or fibromyalgia.
blah-blah-blah
When a trauma occurs, such as a severe infection, a car accident or severe emotional stress, most people eventually recover. But a minority go on to develop a chronic condition such as fibromyalgia. These individuals may be suffering from a genetic protein defect that makes them especially prone to develop hypercoagulability. High lipoprotein(a) also promotes hypercoagulability by blocking fibrinolysis. High homocysteine (over 10) is also associated with with hypercoagulability. High blood sugar and high triglycerides also promote elevated blood viscosity. Thromboxane, an eicosanoid derived through the metabolism of polyunsaturated fatty acids, is yet another factor promoting hypercoagulability. Altogether, the regulation of coagulation is quite complex, involving the balance of more than a dozen factors. It takes special tests to establish if a patient might be deficient in proteins C and S, for instance, or shows elevated fibrinogen.
Hypercoagulability can be easily detected through the use of the well-known "sed-rate" blood test. Sed rate of less than 5 indicates hypercoagulability. The difficulty comes in trying to find out the major factor(s) causing the condition. Thus the need for additional testing, so that the right factor (e.g., high lipoprotein(a) or high fibrinogen) can be targeted for treatment.
Virus infections have been singled out as particularly likely to provoke excess fibrin production. This fibrin accumulates in certain places, creating a "fibrin block" that impedes blood flow and deprives a certain area of the body of sufficient oxygen. Ryser said that she finds a history of two to six serious infections per every chronic fatigue patient. There is also suspicion that certain vaccines can act as precipitating agents for inflammation-induced hypercoagulability (e.g. anthrax vaccine contaminated with mycoplasma, a suspect in the Gulf War Syndrome).
...
Our understanding of the aging process is also enhanced by the perception that impeded blood flow leads to local ischemia (oxygen deficiency), and this is turn translates into progressive tissue atrophy. Only fifteen seconds of ischemia turns off the mitochondria. This initiates an apoptosis (programmed cell death) cascade. The shrinking of our organs with age leads to ever-greater pathology. Loss of heart tissue eventually results in congestive heart failure. Loss of glandular tissue results in hormone deficiencies, loss of neural tissue brings on cognitive dysfunction and eventually senile dementia, loss of lung tissue leads to emphysema, and so on. This is the atrophy of aging that we see throughout the body. The new insight is that "ischemia is a silent cause of aging and degenerative disease."
...
In order to fight ischemia, we need to keep the blood from getting too viscous and sluggish, and platelets from clumping too readily. We now see that various micronutrients are not only antioxidants, but also anticoagulants. Their great advantage is safety. We know how to counteract various procoagulant factors: high homocysteine, for instance, can be remedied through the use of folic acid, B12 and B6; aspirin, curcumin, ginger and ginkgo inhibit platelet aggregation; curcumin is also known to lower fibrinogen.
High lipoprotein(a) responds to niacin (or inositol hexanicotinate), high doses of vitamin C, and the amino acids lysine and proline. Hormone replacement and exercise also help maintain a more youthful blood circulation. Enzymes such as bromelain and Wobenzym have been found to lower blood viscosity. Even massage is seen in a new light when we learn that it helps release tissue plasminogen activator (tPA) from the lining of blood vessels, thus promoting better circulation.
...
they also mentioned heparin and glucosamine as anticoagulants.
---
I would choose natto tho'.
...
I don't know if anyone finds this helpful. Take care
