gbells
Improved ME from 2 to 6
- Messages
- 1,503
- Location
- Alexandria, VA USA
First I'd like to say that I'm extremely frustrated at the lack of progress being made in discovering the pathogenesis and effective treatments for SEID (CFS) and now long covid. In my own case, I have a good history of what triggered it. First I contracted EBV then during the convalescent phase, about six weeks post-infection, I contracted HSV-6 and started showing signs of apoptosis (muscle twitching) that subsided with a lowered body temperature, cold skin and the classic signs of SEID.
What is interesting was that several years later my EBV labs turned negative but HSV-6 remained positive. The explanation for this is that perhaps HSV-6 was able to superinfect previously infected (immortalized) EBV cells, shut down their replication and give a much larger reservoir than a normal HSV-6 infection. This is why in that study on valganciclovir the EBV HSV6 positive patients did better on the drug than the other SEID cases.
If this is what is happening then an effective treatment would 1) stop HSV-6 viral replication and 2) destroy the infected cells or cut out the HSV-6 virus from the cell's DNA.
I have had success stopping the SEID progression and regaining some function by using supplements to unblock HSV6 apoptosis checkpoints but so far I have not been able to make enough progress in the mitochondrial fragmentation fatigue. So far I have been able to.
What is interesting was that several years later my EBV labs turned negative but HSV-6 remained positive. The explanation for this is that perhaps HSV-6 was able to superinfect previously infected (immortalized) EBV cells, shut down their replication and give a much larger reservoir than a normal HSV-6 infection. This is why in that study on valganciclovir the EBV HSV6 positive patients did better on the drug than the other SEID cases.
If this is what is happening then an effective treatment would 1) stop HSV-6 viral replication and 2) destroy the infected cells or cut out the HSV-6 virus from the cell's DNA.
I have had success stopping the SEID progression and regaining some function by using supplements to unblock HSV6 apoptosis checkpoints but so far I have not been able to make enough progress in the mitochondrial fragmentation fatigue. So far I have been able to.
- Cure Raynaud's disease.
- Raise body temperature 0.5 deg F. (97F to 97.5F)
- Almost completely eliminate light and sound hypersensitivity.
- Lower symptoms of depression and anxiety.