Hi
@HABS93 Go habs go!(I live in Montreal and I'm a huge HABS fan 93 was a great year!)
To give you an idea of what oxalates can do I switched to low oxalate diet in June after being paleo/keto for several years.
I'm now on my 21st week of oxalate dumping and it's finally starting to slow down but it hasn't been fun. I have passed kidney stones as well since going low oxalate but I have noticed incredible benefits in mood, energy, joint pain and cognition. I have put on muscle mass and reduced body fat. I can work out now harder than I've ever been able to before because I no longer have joint pain in my shoulders, hips or knees. I haven't had a panic/anxiety attack since eliminating oxalates from my diet.
I have a major problem with oxalates because of several SNPs in that pathway. Oxalates seem to have been a major contributor to my illness. If you are exhibiting high urinary oxalate, you may also have genetic problems in this pathway and if you don't eliminate almonds and spinach (literally the two highest oxalate foods) then you will not heal and will likely only get worse. I eat a lot of meat so that's how I get sufficient protein.
This is a very good article on oxalates. It talks about oxalates effect on glutathione, methylation, yeast etc.
https://www.realizehealth.com.au/2015/12/18/oxalates-yeast-and-mitochondrial-dysfunction/
In my experience, after 10 years of treating myself for CF/ME/Asperger's syndrome, methyl b12 and methylation correction is the best way to increase glutathione and open up detox pathways followed by low oxalate diet and finally iodine and selenium supplementation will also raise glutathione. NAC was pretty good for me as long as I took glycine with it but not as effective as the advanced methylation protocol.