Dr Chia finds tenofovir works for up to 1 in 3 ME/CFS patients. There are a couple of tenofovir success stores in this recovery and improvements thread
Some ME/CFS patients find tenofovir hard to tolerate, and in these cases low doses can be used initially and the dose slowly built up. The full dose of tenofovir disoproxil fumarate is 300 mg daily, but patients often start on an eighth or a sixteenth of a 300 mg tablet.
says, tenofovir alafenamide (TAF) may be safer than tenofovir disoproxil fumarate (TDF), as TAF appears to have less kidney and bone side effects. A dose of 25 mg of TAF is equivalent to 300 mg of TDF. Ref: 1
Tenofovir may be effective against the low-level infections found in ME/CFS. 1
Tenofovir is also effective against human endogenous retrovirus (HERV) infections, 1
which may be active in ME/CFS. 1
HERVs are naturally present in all humans, but are normally inactive; however enteroviruses and EBV can cause HERVs to activate. 1
Tenofovir can cause serious life-threatening side effects, including lactic acidosis, kidney problems and severe liver problems, see here
. When taking tenofovir, regular kidney function blood tests are required.