I have taken it on to help out raising awareness for the immune study in Spain because I believe it is an important study. They are not doing to well with donations the past few days and time is running out. Also my time and energy is very limited, so if some of you could help and repost the links and information on social media it might help.
I compiled all information, which I think is important, to forward.
New Immune Marker Study in Spain
“Characterization of the T regulating cells in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome” is the name of the project we are seeking funds for. The objective of the study is to establish new tools for diagnosing, as well as understanding better the causes of ME/CFS and possible therapeutic directions. This project gives continuity to the study published last year by the same researchers which proves that there are 8 molecular alterations in people with ME/CFS which seem to be related to a faulty functioning of the immune system.
To donate:
http://www.verkami.com/locale/en/projects/8246#
For information from Dr. Blanco directly
For the science interested on the topic "T regulatory cells" and immune markers
I compiled all information, which I think is important, to forward.
New Immune Marker Study in Spain
“Characterization of the T regulating cells in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome” is the name of the project we are seeking funds for. The objective of the study is to establish new tools for diagnosing, as well as understanding better the causes of ME/CFS and possible therapeutic directions. This project gives continuity to the study published last year by the same researchers which proves that there are 8 molecular alterations in people with ME/CFS which seem to be related to a faulty functioning of the immune system.
To donate:
http://www.verkami.com/locale/en/projects/8246#
For information from Dr. Blanco directly
Dr. Blanco: "We also believe that exploring the function of Tregs will help us to understand the origin and to explain the consequences of immunological abnormalities in CFS."
And you talked in your last study about the heterogeneous patient population. Will you be narrowing down this heterogeneity with using a stricter criteria - ME ICC ?
We will analyze the same patients that we characterize in our JTM paper. This approach will allow for a full characterization of these patients (all previously collected data are available)
You also talked about the difficulties with co-infections or opportunistic infections and immune marker testing. Did you, or are you planning to test your patient cohort for opportunistic infections or Lyme ( low CD57 ?). If yes, will you maybe subgroup patients accordingly in concordance with immune marker testing ?
This is one of the reasons to use the same samples. All the data on CD57 and on co-infections will be available and will help us to delineate an almost whole picture of the immune status.
All the best!
And thanks again!
Julia
http://www.mecfsforums.com/index.php/topic,19366.15.html
For the science interested on the topic "T regulatory cells" and immune markers
All three studies found an increased level of Tregs in patients diagnosed with ME/CFS. Regulatory T cells play an important role in maintaining immune homeostasis. Increased levels of Tregs have been found in many cancers and various viral contexts. Tregs are known to cause immune suppression and could explain the other immune abnormalities found in ME patients.
http://www.mecfsforums.com/index.php?topic=16077.0
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