Hapl808 has it right: with any such hypotheses that claim some sort of treatment, you have to consider how many of us have already tried that treatment without finding any change in our ME.
I recently posed a link to a paper about astroglial metabolism. It shows just how complex astroglial metabolism is--converting different fuels into ATP or other fuels for neurons, influenced by many factors--and just how much of an effect this has on the rest of the brain. There seemed to be lots of ways that a subtle dysfunction could result in ME symptoms. That paper didn't suggest any simple ways of affecting that. Furthermore, glial cells are harder to study and harder to influence (the BBB blocks many chemicals). Studying and affecting cell membranes outside the brain would be much easier.
It's definitely not a case of "Cut sugar from your diet and your ME will go away." Too bad.