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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Fairly rapid tissue and muscle wasting during disease onset

L

leokitten

Senior Member
Messages
1,578
Location
U.S.
dom_hend123 said:
@leokitten did you ever figure out the tissue wasting?
Click to expand...

I don't understand the question, the tissue wasting is definitely due to ME/CFS, it's one of my major symptoms. There's no other answer than this. I didn't take any antibiotics before getting ME and I know it's not antibiotic related.

My theory is that we know ME causes a major cellular metabolic block in PDH and aerobic glycolysis (multiple labs and studies have shown this) and our bodies struggle to compensate by initially consuming our tissue for energy, since it's not getting enough from food since PDH is blocked.
 
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