We should all make our decision regarding vaccinations. Yours, Lenora
Since I never suffered the flu without any vaccination (lots of harmless colds though; last 3-day sickness-leave in 2006), the risk of dying my age-group of covid-19 still being less than from the flu, probably had it already very mildly last February in Asia. Addtitionally working in essential infrastructure with immune-compormised clients without any transmissions.
And never in my life having regretting any of my refusals of invasive procedures after conscientious risk/benefit analysis. My dicision of course is already made with any of the until now available experimental vaccines.
continue reading here: Informed consent disclosure to vaccine trial subjects of risk of COVID‐19 vaccines worsening clinical disease (nih.gov)Informed consent disclosure to vaccine trial subjects of risk of COVID‐19 vaccines worsening clinical diseas
Timothy Cardozo1 and Ronald Veazey 2
Aims of the study
Patient comprehension is a critical part of meeting medical ethics standards of informed consent in study designs. The aim of the study was to determine if sufficient literature exists to require clinicians to disclose the specific risk that COVID‐19 vaccines could worsen disease upon exposure to challenge or circulating virus.
Methods used to conduct the study
Published literature was reviewed to identify preclinical and clinical evidence that COVID‐19 vaccines could worsen disease upon exposure to challenge or circulating virus. Clinical trial protocols for COVID‐19 vaccines were reviewed to determine if risks were properly disclosed.
Results of the study
COVID‐19 vaccines designed to elicit neutralizing antibodies may sensitize vaccine recipients to more severe disease than if they were not vaccinated. Vaccines for SARS, MERS and RSV have never been approved, and the data generated in the development and testing of these vaccines suggest a serious mechanistic concern: that vaccines designed empirically using the traditional approach (consisting of the unmodified or minimally modified coronavirus viral spike to elicit neutralizing antibodies), be they composed of protein, viral vector, DNA or RNA and irrespective of delivery method, may worsen COVID‐19 disease via antibody‐dependent
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