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I'm a slow metabolizer. And please make the thread you mentioned; I'm interested
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I'm a slow metabolizer. And please make the thread you mentioned; I'm interested
Indeed. Have you had the HDRI Methylation Panel done yet? I have a consult with my doctor this week, so will be discussing it with him.
Positive in that dbSNP orientation is plus. So if dbSNP DOES correlate to positive for that SNP, then I have serious problems in GSTM1. If I crossreference my above posted results with the dbSNP orientation field, it seems they DO correlate. The field will be plus if you are either homozygous or herterozygous positive for the SNP.
I do hope my interpretation is rock solid, as I'm going to take these results to the doctor with me on Friday. It certainly sheds some light on why I have such a horrendous time supplementing almost anything in relation to the methylation cycle. I'm one of these people whose body rejects almost anything you throw at it.
The annoying thing is, recommendations for the 2 COMT homozygous positive SNPs I have is to supplement hydroxocobalamin -- but -- I suspect my glutathione is likely way too low for the enzyme that activates hydroxocobalamin to methylcobalamin to work, therefore this is kind of useless, but supplementing methylcobalamin will overload me with methyl groups.
Such a painful network in interrelated nightmares.