Based on 19 years with CFS. 10 searching for answers.
But I suspect you're looking for something more 'concrete'.
Read this:
http://hrcak.srce.hr/file/157836
This is a perfect example of common pathophysiology.
With just the right Cytokine profile, one develops symptoms of sickness behaviour which are identical to those of CFS. It took 3 months for cytokine profile to normalise and symptoms to disappear.
The above study is very important and I suggest you read it thoroughly. It relates to CFS a great deal even though it isn't specifically mentioned.
No need to address triggers if cause is eliminated.