in order to make my cannabinoid receptors happy, I simply smeared lecithin on skin. it contains phosphatidyl ethanolamine, which triggers cannabinoid receptors.
(But I can't vouch for pain for the simple reason that I didn't have any to begin with. but cannabinoid receptors are important also for digestion, more specifically to suppress excess inflammation in the gut. the effect was dramatic: I could eat so much more that I even succeeded to gain weight. before that I could eat almost nothing, but after a while I ran into bigger trouble. making cannabinoid receptors happy is only a trick to make the body function more normally than it is able to. for me it worked better to do the hard work to address the underlying causes of my gut problems instead of quick fixes that make me function for a while)
just in case that you are open to an unusual thought - well, unusual only for PR: there is research that spiritual meditation substantially increases pain threshold. this is open to everyone, one does not have to believe in any spirits or gods. (belief is optional. spiritual meditation works with or without. I am a researcher and I don't believe anything unless reasonably substantiated.)
I have tried this spiritual meditation thing and it worked wonders for me with lasting success. the effect becomes stronger and stronger. experienced meditators can even get full happy ecstasy (called ananda in yoga / sanscrit. this is the namesake for today's word anandamide, the most important endocannabinoid), I got this once
Unfortunately it's difficult to measure endocannabinoids in the human brain, which is what would be needed. instead all the research I know measures pain thresholds.
- if any of these are of interest, let me know. I have somewhere the details: the product of lecithin I used, the composition of lecithin and I have somewhere this study on spiritual meditation. can find them in my notes,