I am now about four weeks since starting the methylation treatment. At this point, I already feel about 90% of 100% of what I used to be like (and this is eight years older). I still am getting occasional pain flares in two spots (down from five) and the worst - has been a level 2 (which is NOTHING). My energy level seems like it's completely restored - though to be honest, I haven't been pushing myself very hard. But, instead of spending 16 out of every 24 hours in bed (when I wasn't at work). I'm now only spending 8 hours in bed - and only to sleep. It is AMAZING. I'm just making sure that my after work hours and weekend hours aren't constant labor so that I don't overdo things while I'm still in recovery mode. Having diahrrea 9 days out of 10 to NO DAYS - huge plus. And my numbness & tingling on my right side - gone. Balance issues - gone. My only true complaint these days has to do with recoverying from oral surgery. I am absolutely flambasted by the benefits so soon. And I haven't even fully implemented the protocols. With time and exercise I'm hoping to build my muscles back to full strength and catch up on all the housework that didn't get done for years. .
I see you have two copies of the MTHFR.. Im the same and found that treating this was very helpful and had me heading in the right direction, towards improving, my stamina was even increasing (that is until I did a house move and further crashed loosing then all the benefits of what I'd been doing with the MTHFR treatment).
Take care, its all too easy to go and loose the gains we get from treating something from overdoing things.
He doesn't seem to be following Yasko nor Fredd nor anyone else's recommendations that I've seen. He's more here - lets start with 'x' and then we adjust as needed. I was worried, because with my genes there's some suggestions that I need adenyl or hydroxy B12 and he was fine with me taking a oral supplement that contains methylB12 with the L5Methylfolate and not suggesting I start any sublinguals (well, he hasn't yet). But it's working - so I'm done worrying about it.
Similar with my MTHFR specialist.. he's getting me to have methyl12 (but sublingually) and told me to stop hydroxy B12 which another specialist had me on (the hydroxy B12 had only helped my brain some but did nothing else).. with active folate (previous specialist had me on normal folate which did nothing) and methylB12 thou. We are still currently working towards getting the protocol Im on for this more right (he's going by changes he is looking for in my blood test results).
Its kind of sad that more then 16% of our ME/CFS community would have a double gene of this problem gene and doctors dont routinely test us for it. (the rate for double MTHFR copy varies from 9-16% depending on what country you are in but would be far higher amoung us). We really need to have a study done on MTHFR and ME/CFS rates done.
sorry to take this thread off topic.