I have come back to post again and eat my words!
When I posted on this thread the first time, I'd only been taking curcumin for a short while. Now, I have experimented with taking it daily for quite awhile and seeing my pain level skyrocket, though I had changed no other supps. or drugs. So I would go off for a week or two, and the pain would go away in 24 hrs. of stopping it. I went back on it and then off again, 3 times, and have had to conclude, sadly, that it is the most likely cause of my greatly increased fibro-like pain, up to the point of not being able to walk properly from foot pain and stiffness, and being severely short of breath from the exhaustion the pain caused.
Since I have life-threatening MCS, I am guessing I do have a slow Phase I detox. Is that faulty thinking? So, logically, I am thinking maybe the curcumin is causing a Herxheimer reaction by killing something off....maybe a virus? However, other natural anti-virals, like OLE, caused zero Herx at high doses.
I am very confused and sad, because I love that curcumin raises glutathione and that it helps prevent AZD, which I have a high risk of getting.
BTW, my husband, who has a regional pain syndrome due to his work, is still getting about a 40% reduction in his need for narcotics by taking just 500 mgs. of curcumin daily. (He can't take the recommended 3 x daily dose due to being on blood thinners). We use Jarrow 500 mgs. caps, but because there is no Bioprene in them, always take them with our multivitamin, which does have bioprene.
klutzo