ChookityPop
Senior Member
- Messages
- 605
Would love some thoughts on these results.
Your tests have shown some abnormalities that can be random (and we will therefore repeat some of the tests in about 12 weeks) but it can also not be ruled out that it has to do with your ailments. Though in that case your missing some other classic symptoms that you possibly would expect to see at the results of the tests listed below. In addition, it is important to say that they are a number of people who fail these tests but who do not have any kind of illness.
Samples are repeated within 3 months
Analyzes:
Β-Cardiolipine IgG: 35 (<10),
β-Cardiolipine IgM: 6 (<10),
P-Beta2-Glycoprotein I IgG: 30 (<10),
P-Beta2-Glycoprotein I IgM: <1 (<10),
P-Complement C3: 1.00 (0.70 - 2.00),
P-Complement C4: 0.28 (0.10 - 0.50),
P-C1 inhibitor quantification: 0.27 (0.16 - 0.38),
P-C1 inhibitor function test: 80 (> 68),
P-Terminal Complement Complex SC5b-9: 205 (<300), P-Complement C1q: 152.0 (70.0 - 150.0),
P-Classic activation pathway: 69 (> 40),
P-Lectin activation pathway: 45 (> 10),
P-Alternative activation pathway: 68 (> 10),
CONCLUSION FUNCTIONAL COMPLEMENTARY ACTIVITY: See comment,
P-Albumin (electrophoresis): 43 (40 - 52),
P-Alpha-1-globulin: 2.6 (2.1 - 3.5),
Β-Alpha-2-globulin: 5.8 (4.4 - 7.8),
β-Beta-1-globulin: 2.8 (3.5 - 5.3),
P-Beta-2-Globulin: 2.3 (2.1 - 4.8),
P-Gamma-globulin: 6.5 (7.3 - 14.4),
P-Protein Electrophoresis:
See Comment, P-IgG: 7.7 (6.1 - 14.9),
P-IgA: 0.98 (0.70 - 3.7),
P-IgM: 0.67 (0.40 - 2.1),
P-Kappa chains, free: 11.5 (4.0 - 25.0),
P-Lambda chains, free: 9.5 (6.0 - 27.0),
P-Kappa / lambda chains: 1.2 (0.5 - 1.6),
Β-Cardiolipin IgG:
Weak positive.
P-Beta2-Glycoprotein I IgG:
Positive.
P-Beta2-Glycoprotein I IgM:
Antiphospholipid syndrome (APS) is classified according to international consensus guidelines based on the discovery of either anticardiolipin antibodies, lupus anticoagulant or anti-Beta2 Glycoprotein-1 in addition to clinical criteria. In the event of a positive finding, renewed testing is recommended after 12 weeks. Weak positive anticardiolipin may be transient and due to other conditions (inflammation, infection, malignancy). Findings of several types of phospholipid antibodies (isotypes and specificities) are associated with a higher risk of APS. The level of anticardiolipin antibodies is also associated with increased risk. The 99th percentile for beta-2 Glycoprotein I IgG is 10 U / mL and for beta-2 Glycoprotein I IgM 4.1 U / mL. Reference: Ann. NEW. Acad. Sci. 2009: 1173: 21-27 Villalta et. eel.
However, such percentiles should not be perceived as absolute as the boundaries may vary from experience between different studies.
P-Terminal Complement Complex SC5b-9:
Negative.
P-Complement C1q:
Elevated C1q values have no established diagnostic significance, and may in some cases be due to analytical conditions.
CONCLUSION FUNCTIONAL COMPLEMENTARY ACTIVITY:
Functional complement activity was normal in both classical, lectin and alternative activation pathways. No evidence of complementary defect.
P-Protein Electrophoresis:
Reduced gamma fraction. Monoclonal component not detected.
Your tests have shown some abnormalities that can be random (and we will therefore repeat some of the tests in about 12 weeks) but it can also not be ruled out that it has to do with your ailments. Though in that case your missing some other classic symptoms that you possibly would expect to see at the results of the tests listed below. In addition, it is important to say that they are a number of people who fail these tests but who do not have any kind of illness.
Samples are repeated within 3 months
Analyzes:
Β-Cardiolipine IgG: 35 (<10),
β-Cardiolipine IgM: 6 (<10),
P-Beta2-Glycoprotein I IgG: 30 (<10),
P-Beta2-Glycoprotein I IgM: <1 (<10),
P-Complement C3: 1.00 (0.70 - 2.00),
P-Complement C4: 0.28 (0.10 - 0.50),
P-C1 inhibitor quantification: 0.27 (0.16 - 0.38),
P-C1 inhibitor function test: 80 (> 68),
P-Terminal Complement Complex SC5b-9: 205 (<300), P-Complement C1q: 152.0 (70.0 - 150.0),
P-Classic activation pathway: 69 (> 40),
P-Lectin activation pathway: 45 (> 10),
P-Alternative activation pathway: 68 (> 10),
CONCLUSION FUNCTIONAL COMPLEMENTARY ACTIVITY: See comment,
P-Albumin (electrophoresis): 43 (40 - 52),
P-Alpha-1-globulin: 2.6 (2.1 - 3.5),
Β-Alpha-2-globulin: 5.8 (4.4 - 7.8),
β-Beta-1-globulin: 2.8 (3.5 - 5.3),
P-Beta-2-Globulin: 2.3 (2.1 - 4.8),
P-Gamma-globulin: 6.5 (7.3 - 14.4),
P-Protein Electrophoresis:
See Comment, P-IgG: 7.7 (6.1 - 14.9),
P-IgA: 0.98 (0.70 - 3.7),
P-IgM: 0.67 (0.40 - 2.1),
P-Kappa chains, free: 11.5 (4.0 - 25.0),
P-Lambda chains, free: 9.5 (6.0 - 27.0),
P-Kappa / lambda chains: 1.2 (0.5 - 1.6),
Β-Cardiolipin IgG:
Weak positive.
P-Beta2-Glycoprotein I IgG:
Positive.
P-Beta2-Glycoprotein I IgM:
Antiphospholipid syndrome (APS) is classified according to international consensus guidelines based on the discovery of either anticardiolipin antibodies, lupus anticoagulant or anti-Beta2 Glycoprotein-1 in addition to clinical criteria. In the event of a positive finding, renewed testing is recommended after 12 weeks. Weak positive anticardiolipin may be transient and due to other conditions (inflammation, infection, malignancy). Findings of several types of phospholipid antibodies (isotypes and specificities) are associated with a higher risk of APS. The level of anticardiolipin antibodies is also associated with increased risk. The 99th percentile for beta-2 Glycoprotein I IgG is 10 U / mL and for beta-2 Glycoprotein I IgM 4.1 U / mL. Reference: Ann. NEW. Acad. Sci. 2009: 1173: 21-27 Villalta et. eel.
However, such percentiles should not be perceived as absolute as the boundaries may vary from experience between different studies.
P-Terminal Complement Complex SC5b-9:
Negative.
P-Complement C1q:
Elevated C1q values have no established diagnostic significance, and may in some cases be due to analytical conditions.
CONCLUSION FUNCTIONAL COMPLEMENTARY ACTIVITY:
Functional complement activity was normal in both classical, lectin and alternative activation pathways. No evidence of complementary defect.
P-Protein Electrophoresis:
Reduced gamma fraction. Monoclonal component not detected.
Last edited: