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This is a very minor symptom, but I'm curious about it...for about 4 years I've had one itchy spot in my left calf. It comes and goes, but is always in the same spot, and doesn't seem to be spreading or worsening (although it's pretty bad today!) The weird thing (why I haven't told my doc, bc I have lots of more "normal" symptoms) is that there's no indication on the skin that there's anything wrong--no rash, lesions, discolouration (unless I scratch it too much). Has anyone else ever experienced this?