Did you read the posts by former member Dog Person?
No I didn't. I can't find it. Did he remove it ?
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Did you read the posts by former member Dog Person?
Sorry, I just saw this. I have been spending a lot of time on the Burnout Bench.No I didn't. I can't find it. Did he remove it ?
One of the recommendations for pyroluria is arachidonic acid, a pro inflammatory omega 6 oil that the body produces from linoleic acid and gamma linoleNic acid. They say that people with pyroluria need more of this. I realise that this is true in general and may extend to pple with CFS/ME.
Sometime ago I had ESR (erythrocyte sedimentation rate) tests done. It is supposed to test the body's inflammation responses. My values were always in the single digits 2 or 5 with the normal value starting at 10 or 25. My doctor could not explain this. Back then, I thought that this was a good thing but a healthy inflammation response in also important for the immune system to work well.
Nowadays I take about 200mg of arachidonic acid a day along with gla and aa high foods. It may also be a reason why I am doing better in general. It is worth knowing that in the brain, the ratio of aa to dha is almost one to one.
This is a VERY helpful site.. thanks!I have found this site useful for understanding Liver Detoxification. It seems to have been expanded since last I viewed it. Just try reading a little at a time...maybe...
http://www.tuberose.com/Liver_Detoxification.html
The liver can remove a broad spectrum of microorganisms such as bacteria, fungi, viruses and parasites from the blood
Yes interesting Little Bluestem...so any impairment of the liver including parenchyma, ducts, circulation & supporting structure would impair that function of removing microorganisms.Yes, very helpful. I haven't read it all yet, but I have already learned one new, interesting thing.
I am also wondering, merylg, if long-term microorganism removal could tax the liver and lead to liver impairment.so any impairment of the liver including parenchyma, ducts, circulation & supporting structure would impair that function of removing microorganisms.
So, Alex, are you saying too much Omega 3 is hard on the liver? What's too much? Thanks
I do not think omega-3 is likely to be hard on the liver. It can cause excessive blood thinning, and there is some vague and so far as I know unproven potential to reduce gut healing. Eicosanoids come in three flavours. Series 1, 2, and 3 - they didn't have much imagination. So if you see something like PGE2, thats prostaglandin, E (the type), series 2. The 2 tells you its made from arachidonic acid. Series 1 is made from DGLA which is a precursor to arachidonic acid. Series 3 is from omega-3s. That one is easier to remember obviously.
Now these eicosanids have many functions, from regulating blood vessels to the immune system. Some are pro-inflammatory, some are anti-inflammatory. The balance of pro- and anti-inflammatory factors, including impact from factors that are not eicosanoids, is what determines the level of inflammation. I have not investigated the science behind that recently - and I am sure its very complicated.
Now its a common misconception that omega-3s are anti-inflammatory. They are not particulary anti-inflammatory. They are also pro-inflammatory. The issue though is, I think (doh, its been too long now since I researched this), that an enzyme called cyclooxygenase prefers (preferentially processes) omega-3 fats to omega-6 fats. Omega-3 derived eicosanoids are less inflammatory on the whole than arachidonic acid derived eicosanoids. So when you take omega-3s you still make repair, anti-inflammatory and pro-inflammatory eicosanoids, but the impact of the pro-inflammatory eicosanoids is much less. That decline is a relative decline, rather than an increase in anti-inflammatory action, I think. This science changes so rapidly though, and I am now very out of date, so my explanation should be regarded as tentative.
The take home message though is that arachidonic acid tends to be inflammatory but isn't always. One useful impact of inflammation is to assist fighting off pathogens. So its good stuff in the early stages of infection, and its good stuff in us due to our tendency to be deficient (though this varies patient by patient) but its bad stuff in that it can make us feel more ill and drive inflammation. Its the balance that counts.
Bye, Alex
PS On the liver, one of the main functions of it is to purify the blood coming from the gut, including removing bacterial toxins such as LPS. The fact that LPS is found in our blood tells you the liver is not working properly or is overwhelmed.
I was diagnosed CFS in the early eighties, a heart attack in 1998. Not a candidate for coumadin. Was on aspirin for a few years to thin the blood but gut dysbiosis caused Afib, got off the aspirin, on to fish oil to prevent platelet aggregation and with minerals, controlled the Afib very well. For me, the CFS is all due to dysbiosis in the gut, the propensity of which, is inherited. Now, my liver is in rough shape from so many years of toxins from the gut.
I attribute fish oil for still being alive but I don't think it helped the dysbiosis.