I am not sure about this, even I admit that I would like that what you said to be true. But if it would be true, and if it would be normal a low ratio, then why on the blood test report is given the "normal range" [1 - 3.7]? Consequently my result of 0.69 is not normal according to the report ?!?
On the other hand, I was thinking, could the CD8 increase mean some form of cancer?
Factors that can influence how high or low your CD4 count is....
- CD4 counts tend to be lower in the morning and higher in the evening.
- Acute illnesses such as pneumonia, influenza or herpes simplex virus infection can cause CD4 counts to go down for a while.
- If you have a vaccination or when your body starts to fight an infection, your CD4 counts can go up.
- Chemotherapy can cause CD4 counts to go dramatically down.
- Fatigue and stress can also affect test results.
"Low CD4+ T lymphocyte counts (CD4 counts) are associated with a variety of conditions, including many viral infections, bacterial infections, parasitic infections, sepsis, tuberculosis, coccidioidomycosis, burns, trauma, intravenous injections of foreign proteins, malnutrition, over-exercising, pregnancy, corticosteroid use, normal daily variation, psychological stress, and social isolation."
"Finally, there are a number of people who are completely healthy and who have low CD4 counts for no apparent reason."
"Reports concerning lowered CD4 counts in people who are HIV-negative have been widely ignored. These reports show that CD4 counts commonly fall extremely low, especially if a person suffers from certain conditions. These conditions include a variety of viral illnesses, bacterial infections, parasitic infections, sepsis, septic shock, multiple organ system failure, tuberculosis, coccidioidomycosis, burns, trauma, transfusions, malnutrition, over-exercising, pregnancy, normal daily variation, psychological stress, and social isolation. In addition to lowered CD4 counts, other immune system changes occur that are also identical to those seen in people diagnosed HIV-positive, including reduced CD4/CD8 ratios, increased CD8 cells, reduced lymphocyte function, anergy, increased antibody levels, atrophy of lymphoid organs, and general suppression of cell-mediated immunity. These effects can take weeks or months to return to normal, and, if there are recurrent infections or if multiple factors are present, the low CD4 count could take much longer than this to correct, or may even stay low indefinitely."
"Little is known regarding factors associated with CD4 and CD8 cell numbers in HIV-negative individuals."
"Multivariate analyses of CD8 cells revealed that lower age, higher BMI, Hispanic race/ethnicity; current smoking, injection drug use, and Hepatitis C infection were independent predictors of higher CD8 cell counts. Multiple demographic and behavioral factors may influence CD4 and CD8 counts in HIV-negative women."