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Biomarker found in 2 CFS onset groups NK cells

ljimbo423

Senior Member
Messages
4,705
Location
United States, New Hampshire
From the paper-

Possible ways to enhance NK cell function:

1. Reduce stress,

2. Glutathione – this is needed to produce the chemicals that NK cells release, so low levels of glutathione can lead to reduced NK cell function (Millman, 2008).

Oxidative stress and low glutathione levels have been found in ME/CFS and are suggested as causal factors (Shungu et al., 2012),

3. Supplements – Curcumin, Magnesium, Probiotics, B12, Ginseng, Echinacea, Chlorella, CoQ10 (Ravaglia et al., 2000; Kwak et al., 2012; Currier et al. 2001; Partearroyo et al., 2013; Chaigne-Delalande et al. 2013; Fiala, 2015).
 
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alex3619

Senior Member
Messages
13,810
Location
Logan, Queensland, Australia
In GWI not CFS/ME, if I recall correctly. But I'll have to go back and double check.
You could be right, I would have to recheck too.

PS Just rewatched the video presentation segment, and IL-15 was low in both GWI and CFS. She was not specific about which illness had restoration of NK function, she did not distinguish between them on this issue in the video.
 
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bthompsonjr1993

Senior Member
Messages
175
You could be right, I would have to recheck too.

PS Just rewatched the video presentation segment, and IL-15 was low in both GWI and CFS. She was not specific about which illness had restoration of NK function, she did not distinguish between them on this issue in the video.

So would that mean that IL-15 could be a potential treatment for CFS? Or is it like Ron Davis saying that while certain things return the cells to normal, they aren't safe to be given as medications?
 

Seven7

Seven
Messages
3,444
Location
USA
Is sounds simple, but Klimas (Peterson, and the whole old crew) knew all along about the NK cells, if we could raise it, we would have done so by now, but since I have been in treatment I have not been able to raise w their current options, so hopefully the break through is in how to raise NK via IL-15 since the other info is very old news.
 

Wolfcub

Senior Member
Messages
7,089
Location
SW UK
Thanks for posting this, @Belbyr I am starting at the bare beginning as have only been unwell just over 5 months. I need to start at the beginning with so many things. So it's helpful.
 

bertiedog

Senior Member
Messages
1,736
Location
South East England, UK
Is sounds simple, but Klimas (Peterson, and the whole old crew) knew all along about the NK cells, if we could raise it, we would have done so by now, but since I have been in treatment I have not been able to raise w their current options, so hopefully the break through is in how to raise NK via IL-15 since the other info is very old news.

I was thinking the same thing. I have watched some many videos over the years from Nancy Klimas explaining the situation regarding low Natural Killer Cells in ME and the latest video posted here on PR today was all about this again. She seemed to be quite sure though that she had some ideas as what might help them to become more "normal"

Pam
 

Shoshana

Northern USA
Messages
6,035
Location
Northern USA
Ok, thank you @hamsterman
My thinking was that there are possible or likely, more than 2 sub-groups, so that is why I was confused.

But those 2 onset types. Ok.
That helps my thinking.