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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Thanks for all the interesting & helpful info Cort.
One thing that worries me about the GWS study, is that I thought it was widely understood that some GWS patients never went to war, but still became ill... Some soldiers with GWS participated in all of the preparatory activities for war, and received vaccinations etc., but did not go abroad or go to war. I thought that was the current understanding about GWS anyway. I've definitely read about it somewhere.
In which case, I would have thought that it wouldn't be likely that Uranium was a factor.
Thanks Cort, very interesting studies and information. Also under Dr. Englander in NY another researcher Eric Shaudt Phd. is looking at genomic systems as well using cutting edge technologies to see the systems involved with our disease.
Thanks Cort for bringing this up and the clear description of this research.
"I remember reading something about heat shock proteins in a thread a while back that made sense and fit in with the mitochondrail dysfunction"
Is this the thread Justy?
http://forums.phoenixrising.me/show...xidative-Stress&highlight=heat+shock+proteins
On a quick re-read we were discussing epigenetic mechanisms rather than genome instability but a similar idea.
"In which case, I would have thought that it wouldn't be likely that Uranium was a factor"
Bob
This recent paper by the Gulf War researcher Beatrice Golomb implicates oxidative stress and mitochondrial injury as the core pathology in Gulf War Illness in response to a wide range of toxins/stressors including radiation. She also extends this model to other 'overlap' illnesses including CFS :
http://precedings.nature.com/documents/6847/version/1
The amount of uranium in air is usually very small; however, people who work in factories that process phosphate fertilizers, live near government facilities that made or tested nuclear weapons, live or work near a modern battlefield where depleted uranium weapons have been used, or live or work near a coal-fired power plant, facilities that mine or process uranium ore, or enrich uranium for reactor fuel, may have increased exposure to uranium. Houses or structures that are over uranium deposits (either natural or man-made slag deposits) may have an increased incidence of exposure to radon gas.
Berg D, Berg LH, Couvaras J, Harrison H. Chronic Fatigue Syndrome (CFS) &/or Fibromyalgia (FM) as a variation of Antiphospholipid Antibody Syndrome (APS): an explanatory model and approach to laboratory diagnosis. Blood Coagul Fibrinolysis. October 1999;10(7):435-438