I was asked to share my experience here.
I tried high dose methylprednisolone 160mg for 10 days and it gave me flu like symptoms and made my pots worse (and other symptoms related to dysautonomia i assume, like making my vision more blurry and had more frequent palpitations). It also give me tingling in the extremities while exhaling. I felt like it was making me all around worse and had no benefit (aside from the psoriasis improving) so i stopped it quickly.
I also tried various microglia inhibitors (LDN, boswelia, homotaurin, Palmitoylethanolamide +Luteolin and maybe others i dont remember) and they all gave me flu like symptoms (aside from LDN which didn't give me flu like symptoms but i still felt overall sicker).
I also tried local anti inflammatories for the gut (budesonide, mesalazine) and those didn't give me any change (good or bad).