Aluminium in vaccines linked to new post-vaccine syndrome

[Thomas]

@NK17 I have a keen interest in this topic as my ME was triggered by a flu vaccine in November 2011. I also had Hep B and Hep A vaccines as a teenager with no immediate reactions (I am 35 years old now). Also, my parents are Israeli and have a sort of proud bias towards any science coming out of Israel, so when I showed them the work of Dr. Shoenfeld they were quite intrigued.

Anyways, I think I posted a thread a while back asking if anyone had seen him in Israel or spoken to him from abroad. Do you know if he considers classic ME to fall under the ASIA spectrum? Has anyone been treated by him? You seem to have a great handle on his work and I'd love to learn more...

 

[jepps]

This is an article, that explains a possibility, how aluminium in vaccines could effect the brain:

http://articles.mercola.com/sites/a...0329Z2_SNL_NB&et_cid=DM72743&et_rid=894334310

Dr. Tomljenovic about vaccine adjuvants in general, and aluminium als adjuvants. Dr. Tomljenovic is a post-doctoral fellow at the University of British Columbia (UBC), where she works in neurosciences and the Department of Medicine.

It's sobering to realize that when the aluminum adjuvant was first approved for use in vaccines, some 90 years ago, it was approved because of efficacy. It was never actually tested for safety. Even the total allowable limit was based on efficacy data, not safety data. They just assumed it was safe.

Together with Christopher Shaw, a professor in the department of ophthalmology and visual sciences at UBC who also chairs the CMSRI's scientific advisory board, Dr. Tomljenovic has published a number of papers2,3,4,5,6 that suggest aluminum-containing vaccines may be unsafe.
Not surprisingly, their work has been heavily criticized. The UBC, however, has defended and stands behind Shaw's and Tomljenovic's work on aluminum toxicity

In one of their studies,8 Shaw and Tomljenovic injected mice with aluminum at the equivalent dose given to American children through vaccines, and they spaced out the injections based on the mice's developmental stages. (On a side note, to find out how much aluminum you or your child actually receives from various vaccines, see this vaccine excipients list.9) What they found was that once the mice reached adulthood (which occurs at the age of six months), the treated mice had permanent behavioral impairments.

There was a significant increase in anxiety and a reduction in exploratory behavior. There was also a reduction in social interactions between the mice. "That was a huge confirmation that our initial assumption or correlation [between the number of vaccines and rising autism rates] might be something more than just correlation," she says.

After that, the duo went on to do some gene-based studies, specifically looking at the expression of genes in the mouse brain. They selected 17 candidate genes that are involved in neural function and immune response, and looked to see if there was any change in their expression either at the gene level or the protein level. Here, they discovered:10

• A significant increase in tumor necrosis factor alpha (TNF-alpha) interferon gamma (IFN-gamma), and a chemokine called macrophage chemoattractant protein-1 (MCP-1), which is a macrophage-attracting factor. These are indicative of an inflammatory response in the adult mouse brain
• A significant decrease in a neurotransmitter called acetylcholinesterase (AChE), which is related to depression and anxiety

The changes seen at the genome level and the behavioral level are consistent with findings from studies done on deceased autistic patients, in which chronic brain inflammation was identified. It's important to realize that autism is not just a brain disorder; it's also an immune system disorder. Dr. Tomljenovic calls it an immune system brain disorder, as the two systems are connected.

"The backbone of this research was done 30 years ago. We already knew that there is a significant connection between the immune system and the central nervous system. They communicate. You cannot influence the immune system at the periphery without changing something in the brain. Most of us know that from experience, because when you get the flu, your brain doesn’t function very well. That mental fogginess and chronic fatigue, they are clear neurobehavioral changes in response to an immune stimulus [infection].

It's a neuroendocrine axis—basically, the immune system at the periphery and the central nervous system talk to each other. Again, if you increase an immune response artificially at the periphery, you are going to mess up the brain. They’ve done that artificially using what they call viral and bacterial mimics. I thought, “Oh, that spells like antigens in vaccines,” Because that’s exactly what’s being used. Commonly in this type of research strong adjuvants are added to exaggerate the immune response...

There is a huge body of research that shows that if you overstimulate the immune system at the periphery, especially in the critical stage of early development, you are going to influence the brain in a negative way, and by doing so, you can create irreversible damage. Again, this is research that is rarely discussed, because it really shows that there is reason to question the safety of the burden of vaccines given to infants.”

What this means is that even if they replaced aluminum with another adjuvant, you’d still get the same problem. This is undoubtedly a problem of enormous proportions for the vaccine industry, which explains why this kind of research isn’t done on a routine basis, and why Shaw’s and Tomljenovic’s work is under such heavy fire.

The pair has also investigated the cross-reactivity between the antibodies that are raised against vaccine antigens. As it turns out, some of them cross-react with our own tissues. Many viruses and bacteria share genetic similarities with human proteins.

For example, there may be a peptide sequence in the wall of the virus that mimics the structure of a human protein. So, the antibody that is raised against the virus will then also recognize these epitopes in your own tissues that mimic the virus. This has the potential to cause severe harm, and can significantly raise the risk of autoimmune disorders.

A team from Créteil and the INSERM Institute in France also presented data from animal experiments at the Japanese symposium, which show that if you inject the aluminum adjuvant, a portion of the aluminum is engulfed by macrophages. Some of these macrophages eventually find their way into the mouse brain.

The transport in the brain is dependent on the same chemokine, MCP-1, macrophage chemoattractant protein that Shaw and Tomljenovic found increased in their aluminum-exposed animals. Part of the problem is that the aluminum accumulates, and it stays in the brains of mice up to one year after injection because there’s no recirculation to take it out.

“This is a common problem with aluminum, because it’s got a strong positive charge, 3+,” Dr. Tomljenovic says. “What other research has found is that in Alzheimer’s patients, the chromatin fractions in the nucleus of the cell, where your genetic material is stored, accumulate aluminum. Because the DNA has a negative charge on the outside, it binds the positive aluminum.

Thus aluminum disrupts the chromatin structure and in the brains of Alzheimer’s patients it was found that aluminum binds to selective promoter areas of genes that encode proteins that are essential for neural function. In this way aluminum inhibits the expression of these genes.

Again, the problem is that once the aluminum gets into the nucleus of the cell, there is no way of getting it out. It just stays there. The finding by the French team is that even the aluminum you inject in the periphery can get into the brain, which is a concern...

The fact is that the aluminum we get from vaccines is not rapidly excreted, and most of it does remain in your body because it bypasses the gastrointestinal system. If aluminum was rapidly excreted, as the health authorities would like us to believe, then it would be a pretty lousy adjuvant.”

I want to stress the point Dr. Tomljenovic makes about the harm produced by stimulating an exaggerated immune response, which is what vaccines are designed to do—this is the function of the adjuvant. The problem is, even if aluminum is removed from vaccines, the risk of immune system brain disorder remains even if the new adjuvant is non-toxic. As she explains, by the virtue of over-stimulating your immune system, you run the risk of breaking self-tolerance. Research supporting this was also presented in Japan during its governmental hearing on HPV vaccines.

What the team of Japanese researchers led by Dr Shunichi Shiozawa found15 is that the repeated stimulation with the same antigen overcomes the genetic resistance to autoimmunity. At present, we’re giving children booster shots at regular intervals with the same antigen. And the research shows that when you do this—when you stimulate the immune system on a regular basis—you break the tolerance to autoimmunity. This is a really crucial piece of information that people need to become aware of.

 

[natasa778]

I want to stress the point Dr. Tomljenovic makes about the harm produced by stimulating an exaggerated immune response, which is what vaccines are designed to do—this is the function of the adjuvant. The problem is, even if aluminum is removed from vaccines, the risk of immune system brain disorder remains even if the new adjuvant is non-toxic. As she explains, by the virtue of over-stimulating your immune system, you run the risk of breaking self-tolerance. Research supporting this was also presented in Japan during its governmental hearing on HPV vaccines.

Cue the resistance of regulatory agencies to demand safety studies on cumulative and additive effects of multiple and repeated vaccinations in children or adults, short or long term. There is absolutely zero research on this. We are supposed to 'believe' whatever multi-vax schedule they come up with is kosher for everyone, healthy or not, a belief based on zero data.