- Messages
- 15
- Location
- Atlanta
Hi Everybody -
I am not new to trying to fix my broken down health situation, but I AM new to looking at it from a methylation viewpoint. As you know, there is a LOT to it, and I figured I would throw my info up here and see what you guys might have to say -
To make a super-long story JUST long:
I am:
-a 43 year-old male.
-25 year history of depression, LOTS of counseling over the years - helps a little
-SSRI's have helped somewhat over the past 15 years, but a more recent ADHD meds regimen had made a BIG POSITIVE (if unpredictable) difference over the past few years, at least before my health crashed, anyway
-PLENTY of silver amalgams as a kid, ALL of which were replaced over the years (NOT safely, BTW) before I was aware that mercury was so bad for you, etc.
-TICK BITE 4 years ago - thus Lyme disease for the last 4 years, along with the usual other stuff - probable leaky gut, candida, (yes I took abx for a while, IV also.....) sinus staph infection ongoing.
I have done my own research and treatment for lyme disease constantly for the past 4 years. I JUST stumbled on some more info about methylation, the inexpensive genetic testing available now, etc. The more I read, the more "suspicious" I was about ME and methylation, etc. For the lyme AND for the depression, etc.
**Several months ago, I added in a VERY basic "methylation" protocol to my other supplements, and this seemed (possibly?) to help with my mood a little bit, albeit very unsteady.
** The Lyme was worse "physically" earlier on, but now is hardly a problem at all, except for treatment/medication reactions, HOWEVER,the neuro problems are worse than ever!! Memory issues, depression, anxiety, etc. I am MOST concerned about neuro-transmitters in all of this!!
I am attaching my 23andMe results that have been run through the livewello analysis. Of course there are a lot of problems there, starting with +/+ for A1298C ....
ALSO, I recently got a BUNCH of bloodwork done. Looking at some of those results, especially in light of my methylation status, seems to reflect a LOT of possible correlations. Here are a few of those results:
-LOW serotonin: 26 (ref is 56-244ng/mL)
-HIGH ammonia: 71 (ref is below 47 umol/L)
-HIGH homocysteine: 8.4 (ref is SUPPOSEDLY less than 11.4 umol//L)
-CD-57 (""lyme test""): 68 (ref is 60-360 u/L
-LOW NK (Natural Killer) Cells: 10 (ref 8-170 LU30)
The bloodwork also indicates that there are also a lot of other infections that are having their fun with me:
Parvovirus: 6.6 (ref is less than 0.9 )
Cytemegalovirus - positive
Ebstein Barr virus
Herpes6 - supposedly interpreted as a "past infection"...?
C. pneumonia IGG
Eosinophil cationic prot.: 15 -- indicates possible babesia, reportedly
Candida Albicans: IGG and IGA, both high
I have a LOT of other bloodwork, etc., but those are just the basics.
---------------------------
So far, I've been reading some Yasko, Ben Lynch, and a bit of Rich's info. I spoke to Caledonia too, which has been helpful. She pointed out a few a few tests I might consider, and ways to get going with gut health as a place to start. I would guess FOR SURE that leaky gut is a problem too.
I would still say that I am pretty OVERWHELMED with all of this info. I am also very interested in Freddd's info, although I am still just trying to figure out where to even START with that!!!
While it sounds like these issues have to be addressed in order, understandably, I DO recognize that the neuro-cognitive/depression/anxiety issues are CERTAINLY the hardest to live with, and I would love to target those as soon as possible, and/or maybe find other ways to support them meanwhile. I would really LIKE to get off of the ADHD regimen, largely because my profession has random drug testing, so I will HAVE to get off of those meds before I get back to my regular work...
I have a LOT of other testing results over time, so feel free to ask if it might help....
THANK YOU, everybody, and for what its worth, I REALLY appreciate these sorts of forums where some of us who really need help can "combine forces" and help each other out, in a way that NEVER happens in the usual """medical community"""!
-JR
I am not new to trying to fix my broken down health situation, but I AM new to looking at it from a methylation viewpoint. As you know, there is a LOT to it, and I figured I would throw my info up here and see what you guys might have to say -
To make a super-long story JUST long:
I am:
-a 43 year-old male.
-25 year history of depression, LOTS of counseling over the years - helps a little
-SSRI's have helped somewhat over the past 15 years, but a more recent ADHD meds regimen had made a BIG POSITIVE (if unpredictable) difference over the past few years, at least before my health crashed, anyway
-PLENTY of silver amalgams as a kid, ALL of which were replaced over the years (NOT safely, BTW) before I was aware that mercury was so bad for you, etc.
-TICK BITE 4 years ago - thus Lyme disease for the last 4 years, along with the usual other stuff - probable leaky gut, candida, (yes I took abx for a while, IV also.....) sinus staph infection ongoing.
I have done my own research and treatment for lyme disease constantly for the past 4 years. I JUST stumbled on some more info about methylation, the inexpensive genetic testing available now, etc. The more I read, the more "suspicious" I was about ME and methylation, etc. For the lyme AND for the depression, etc.
**Several months ago, I added in a VERY basic "methylation" protocol to my other supplements, and this seemed (possibly?) to help with my mood a little bit, albeit very unsteady.
** The Lyme was worse "physically" earlier on, but now is hardly a problem at all, except for treatment/medication reactions, HOWEVER,the neuro problems are worse than ever!! Memory issues, depression, anxiety, etc. I am MOST concerned about neuro-transmitters in all of this!!
I am attaching my 23andMe results that have been run through the livewello analysis. Of course there are a lot of problems there, starting with +/+ for A1298C ....
ALSO, I recently got a BUNCH of bloodwork done. Looking at some of those results, especially in light of my methylation status, seems to reflect a LOT of possible correlations. Here are a few of those results:
-LOW serotonin: 26 (ref is 56-244ng/mL)
-HIGH ammonia: 71 (ref is below 47 umol/L)
-HIGH homocysteine: 8.4 (ref is SUPPOSEDLY less than 11.4 umol//L)
-CD-57 (""lyme test""): 68 (ref is 60-360 u/L
-LOW NK (Natural Killer) Cells: 10 (ref 8-170 LU30)
The bloodwork also indicates that there are also a lot of other infections that are having their fun with me:
Parvovirus: 6.6 (ref is less than 0.9 )
Cytemegalovirus - positive
Ebstein Barr virus
Herpes6 - supposedly interpreted as a "past infection"...?
C. pneumonia IGG
Eosinophil cationic prot.: 15 -- indicates possible babesia, reportedly
Candida Albicans: IGG and IGA, both high
I have a LOT of other bloodwork, etc., but those are just the basics.
---------------------------
So far, I've been reading some Yasko, Ben Lynch, and a bit of Rich's info. I spoke to Caledonia too, which has been helpful. She pointed out a few a few tests I might consider, and ways to get going with gut health as a place to start. I would guess FOR SURE that leaky gut is a problem too.
I would still say that I am pretty OVERWHELMED with all of this info. I am also very interested in Freddd's info, although I am still just trying to figure out where to even START with that!!!
While it sounds like these issues have to be addressed in order, understandably, I DO recognize that the neuro-cognitive/depression/anxiety issues are CERTAINLY the hardest to live with, and I would love to target those as soon as possible, and/or maybe find other ways to support them meanwhile. I would really LIKE to get off of the ADHD regimen, largely because my profession has random drug testing, so I will HAVE to get off of those meds before I get back to my regular work...
I have a LOT of other testing results over time, so feel free to ask if it might help....
THANK YOU, everybody, and for what its worth, I REALLY appreciate these sorts of forums where some of us who really need help can "combine forces" and help each other out, in a way that NEVER happens in the usual """medical community"""!
-JR