ron davis

They found the IDO2 enzyme in "insane amounts" in Long Covid patients in all kinds of cells causing "a kind of collective suicide" as well as impaired mitochondrial function and Krebs Cycle dysfunction. They say it's clear that IDO2 continues to rage after the virus is defeated and IDO1...

Doesn't 2023 feel wholly different with respect to covid? While the country was obsessed with this virus for almost 3 years, especially that first year with lockdowns and 24/7 news coverage, etc, 2023 just has a very different feel. On some days I even forget about it. Offices are calling us...

Itaconate Pathway - Called a Shunt, Interrupts citric acid cycle bleeds it off into other uses so it doesn't get into ATP, its for infection fighting. Makes you tired and low energy. What if it doesn't turn off? Issue is its not in all cells. Have to look at RNA signatures. Assay for that RNA...

https://openletteropenmedicinefoundation.com/an-open-letter-to-the-open-medicine-foundation-by-kaylin-jones/ Another person asking the OMF to look into mold or environmental toxins in ME/CFS. So far they haven't responded. But lets keep trying. If anyone else has experienced environmental...

Abstract One in four myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients are estimated to be severely affected by the disease, and these house-bound or bedbound patients are currently understudied. Here, we report a comprehensive examination of the symptoms and clinical...

https://openletteropenmedicinefoundation.com/concrete-demands-for-the-open-medicine-foundation-and-other-me-cfs-researchers/ This website has much info, but this specific part with very specific demands about what kinds of research I would like to see done, I think may be the most important...

https://www.fox5dc.com/news/scientist-with-son-who-suffers-from-chronic-fatigue-syndrome-hopes-research-can-help-covid-19-patients Just a basic interview, no new info, but nonetheless informative. Dr. Davis goes over his credentials, how he got into ME/CFS research, Covid & ME/CFS simmilarties...

So the Nanoneedle electrodes measure the impedance of the blood plasma and everything that’s in it, right? Before the measurements are commenced, NaCl is added to the plasma as a stressor. In the control sample with plasma from a healthy person, impedance is unchanged over time. In the blood...

I still think the metabolic trap theory has some merit. Robert Phair looked into genetic problems and his current theory is that tryptophan metabolism gets overloaded and we don't have the ability to process it and so we get stuck in a trap. The enzyme which can process it is IDO1, as we lack...

Finally, serious research is being deployed into physical causes of ME/CFS, giving hope to many who had given up hope for a better future and had resigned themselves to a life of ill health with very little prospect of improvement. I for one am very happy that serious research is being...

New PNAS paper from Ron Davis and team released ahead of print (not open access). https://www.pnas.org/content/early/2019/04/24/1901274116 ABSTRACT. There is not currently a well-established, if any, biological test to diagnose myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The...