• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. Lolinda

    Increasing mitochondrial energy production using 4 labtests, by Chris Masterjohn - I got out of ME and resolved low ATP

    A PhD's Secret Weapon: The Four Biomarkers Every Expert Should, But Doesn’t, Analyze text version: https://chrismasterjohnphd.substack.com/p/how-to-interpret-ketone-ratios-and Chris Masterjohn presents in this video / article that one needs to measure two ratios: lactate : pyruvate beta...
  2. C

    Help Needed - Normal B12, low everything else

    Hi everyone, I hope you are doing well, or are on the path to it. I've been struggling a lot and I find a lot of advice to be mixed. I think the difficulty is that each of our deficiencies are a little different from the next, so advice isn't perfect. Every test I've done shows normal B12...
  3. gbells

    Epstein Barr virus causes megaloblastic anemia (methylation related)

    I was troublesheeting a high MCV on CBC labs and learned that Epstein Barr virus causes it (megaloblastic anemia). It is a deficiency of activated folic acid and activated B12. I am heterozygous for MTHFR deficiency but never had a problem with it before EBV infection in 2008. Post infection...
  4. Y

    Methylfolate causing inflammation behind nose?

    Brief Background: 31/Male, MTHFR A1298C GG, Anxiety, ADHD, I don't believe I have MS/CFS Both methyl-folate and folonic acid initially make me feel great, but then cause inflammation right behind my nose and seemingly in my general nasal/sinus tract. It also happens even with cofactors/methyl-B...