International ME/CFS and FM Awareness Day Is On May 12, 2018
Thomas Hennessy, Jr., selected May 12th to be our international awareness day back in 1992. He knew that May 12th had also been the birthday of Florence Nightingale. She was the English army nurse who helped to found the Red Cross as well as the first school of nursing in the world.
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Need good info on Vasoconstriction, NADH, B3

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by OneToughCanary, Jun 13, 2018.

  1. OneToughCanary


    I'm still experiencing a lot of achiness as I try to ramp up slowly on MB12 and MFolate. I don't *think* it's a methyltrap or overmethylation symptom, and the addition of B1/Thiamin hasn't seemed to meet the need. I'm thinking, per @Critterina 's advice, I may be needing NADH or B3. I'm beginning to think my achniness and other things, like a hard feeling in my gut and tingly fingers and toes, is from vasoconstriction. I'm trying to learn more but am not finding a lot of real meaty info...and my brain is challenged, perhaps because of vasoconstriction as well, so any hand-holding or help with locating key links is appreciated.
    Some of my questions are:
    * Should one take B3 only when overmethylated, to absorb methyl groups, or is it advisable to actually take B3 in tandem with working on upping methylation? (...but it would simply require that you keep upping the methylators to keep pace?)
    * Any thoughts on what causes vasoconstriction when starting a methylation protocol so that I may get my brain around how to navigate this?
    * Any info on the usefulness and place of NADH?

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