@amaru7 - I had problems with toxic overload for years and it finally resolved with the use of 3 amino acids: glycine, inositol and glutamine. In 2003 or 2004, my digestion was very screwed up, felt tired, sluggish, fluish, couldn't eat until after 12:00 noon. My chiropractor who does muscle testing told me my liver was overloaded with toxins and that's why I felt so sick. I had had a job many years before with heavy exposure to acetone and other chemicals and that seemed to be the problem. I did a liver detox under his supervision, it lasted 30 days and was rather rough but at the end of it my digestion was much better. I also started taking betaine HCL with meals and milk thistle for liver support. Also, before the detox, one glass of wine would leave me feeling sick for an entire day, and 2 glasses would make me sick for 3 days. And after the detox, I could tolerate wine again in moderation.
However, symptoms of toxicity would recur seemingly out the blue j- I would feel sick again, etc., and then usuaslly was able to tie it to something I had ingested - e.g., apple cider vinegar is supposed to be very good for digestion but it left me feeling sick, and then I read that ACV has "cleansing" properties. Anything that was supposed to be cleansing generally made me feel sick. I believe I was retoxing - the ACV etc. would get toxins mobilized out the cells, but they weren't getting out of my body and were just recirculating.
Also, I had had 9 or 10 amalgam mercury fillings which were removed in 1997 I think, so I think I had a load of mercury as well as other stuff. Sometimes my toxic symptoms were feeling spacey, actually felt like I had smoked pot or something and I was pretty sure this was mercury.
Over a period of several months (maybe a year? can't remember) I started taking glycine, inositol and glutamine (not all at once) = e.g., I took glycine for sleep - it helped a lot but it gave me a huge detox reaction. I had to cut my dose way down but kept taking it because it helped with sleep. Inositol also helped with sleep, but also made me detox, though not nearly as much as the glycine. And then I took glutamine (it was part of a BCAA combo) and again, the familiar detox symptoms appeared. But I kept up the glutamine too.
After some months of all of this I realized that I had stopped detoxing. I was no longer reacting badly to these amino acids and also could tolerate ACV (I use it on salads). I hardly ever get detox symptoms any more, and they had been a huge problem for years. I found this article about Phase II liver detox very interesting - it mentions glycine, inositol and glutamine as being necessary for phase II detox, as well as several other nutrients.
https://www.diagnose-me.com/treatment/liver-detoxification-phase-II-support.php
I don't know why so many people insist that detoxing is a myth. Hangovers are a form of toxicity, and if your liver is not up to par, you're going to get pretty sick from alcohol. Too much Tylenol can destroy the liver quite easily. Anyways, I didn't read about detoxing and then start looking for symptoms. I had pretty strong symptoms and then discovered what was causing them, thanks to my chiropractor.