If not, why not? OK, the reason I ask is that it seems to be the cheapest, easiest, and safest way to get high doses into the bloodstream, but the fact that I don't hear more of you all doing it is making me wonder just how effective it is. So far, Ahmo seems to be the only person here who is committed to DIY transdermal B12. I've been using Ahmo's technique (with a couple of tweaks to it), but I still haven't gotten noticeable responses to the B12. However, I'm not sure if I have ever gotten much of a response to the b12, except when I first started on it, so I feel I am not a good guinea pig for this. I plan on upping my dosage in the next week, and maybe this will give me more info. Just fyi, this is the my version the transdermal b12: 1/2 squirt of Bluebonnet 5000 mcg b12 mixed with 1/2 teaspoon Everclear, 190 proof (ethanol helps the b12 to pass through, supposedly--hat tip to @Hip for this info). I smooth that on the skin, then before it is dry I dip my fingers into some sunflower oil (expeller pressed, organic) and rub that on top until the whole thing pretty much disappears. Then, I'm careful to rinse off my hands, because I don't want whatever b12 is left on the skin on my hands to be exposed to light. I do this twice a day (so, 5000 mcg total). I know that at least some of the b12 is getting through, because the first couple of weeks I wasn't so careful about not exposing the b12 to light and I ended up with some nasty lesions on my face from the degraded b12.