• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

WMLs and Post Concussion Syndrome - ME connection?

Hello all, wanted to check in with a question. Some may recall my (34F) posting last year about the discovery of white matter lesions on my brain MRI. Well, since then, I have been on a very strange journey... where I went to a specialist cognitive assessment clinic and their neuroscientists declared that this was actually connected to a collection of concussions I've had in my adult life (which is fact but no one has ever thrown around the words Post Concussion Syndrome before). I know there's been some discussions of others with ME/CFS getting WMLs on their scans, but I am unsure if there's anything out there connecting ME/CFS with TBIs or mTBIs?

Anyone have any idea? Could ME have weakened things enough to where I would be more susceptible to neurovascular injury?


Senior Member
U.S., Earth
I don't know if it helps, but you may be interested in these discussions:

White Matter Lesions?!

Post-Concussion Syndrome may come with PEM

I have heard some doctors say that concussions may predispose someone to getting ME, and others consider Post-Concussion Syndrome to be a type of ME, so the exact relationship between concussions and ME is currently unsettled...
Thanks. What's interesting about this I was actually first diagnosed with ME when I was approx 15-16, and didn't sustain anything relating to head injury until I was an adult. So the ME actually came first in my case. I will check the other discussions.