Welcome to Phoenix Rising!
Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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This guy is now in control at the nhs despite either being incredibly stupid or incredibly evil.
I agree with what @Husband of of says, unless studies become more specific it'll be hard to find anything. I'd much rather see a new study saying 50% of people with ME/CFS have this and this and there are tangible difference amongst these people, rather than we used some ML classifier and obtained a 100% accuracy within our study and we don't know why and no other data will ever be touched.
but that is just one country. there are 100s of other countries. Where the Simon Wessleys' should not be running the show. Yes, I understand there is MORE than one of THEM.This guy is now in control at the nhs despite either being incredibly stupid or incredibly evil.
I doubt it. Nobody is following up on the Subsequent Work necessary for anything to become a bio marker.I expect they've ruled out all the obvious potential biomarkers,
if thats the case, there will be no forward progress.For cfs, based on its current definition, never. And, unfortunately, that's what test for potential biomarkers are being measured against.
And what good would a biomarker do us? When treatment is close to zero, or mostly n=1.
yeah, I realize thats likely the case....The biomarker is incredibly useful for developing treatments.
I'd vote for more of that....particularly ones that respond to treatment
agree..so fed up with this part. FIND SOMETHING MEASURABLE and replica table."Do you feel better?"
It would be easy to mix up MS and ME/CFS and LC and fibro and so forth.
I hope you are right but I don't really see this for biomarker studies. What I see is some studies that hypothesise about causes may suggest there are different subsets.How many ME research studies say: for a SUBSET of patients, X or Y is going on....(many many say this)
Yes. I feel like a vascular marker might be possible within the near future. Some inflammatory vascular markers as well as markers of endothelial dysfunction have received quite a lot of attention, especially in Long-Covid. This probably won't be unique to the disease, might not be applicable to everyone and might not be the root cause, but a biomarker isn't a solution for other diseases either, it's just often just a necessary first step that, not only shows some physiological properties of the disease that can be aimed to be untangled, but casts a large shadow on its psychologization.It's just not as simple as "finding a biomarker = problem solved",