What possible cure/treatment/research excites you the most?

[marlunette]

I guess all the main root cause analyses are interesting. CDR theory does interest me a lot, even if it sounds non specific and maybe a bit of a stretch. I find the sumarin treatment theory very interesting too.

Suramin sounds so tantalizing because it's already in production, considered quite safe, and in theory only has to be used for a few rounds. CDR is the most exciting theory to me because it allows for multiple triggers and takes into account the complexity of our bodies.

 

[godlovesatrier]

@marlunette Yes I agree. I've just been re-reading it all. It's going to be an interesting one and such small doses would be needed as well. Let's hope it works in the autism trials again and then they can do the ME trial next year. Fingers crossed covid doesn't mess that up.

 

[JES]

But that was just the population in the study, "data of 20 severely ill patients". It maybe that they have no bearing on the rest of the ME/CFS community and/or just a proportion, a subset?

They have tested more than that now, I think the latest number was around 60 or 70, out of which all except for one had genetic mutations that made IDO2 non-functional, and the one patient they weren't 100% sure he/she didn't also have some other damaging mutation in the same gene. Hopefully they'll give an update on this again soon as those numbers were from last year.

I'm mostly excited about the kynurenine trial, some Lyme recovery stories from using disulfiram and also any upcoming antiviral compounds, but it seems to take its time. The drugs that showed a response in the nanoneedle are for sure interesting, but I'm less optimistic about availability, cost and side effects (with given dosage).

 

[Treeman]

For me Prusty's work and Naviaux theory of cell danger response aim to get to the root of the problem, are complementary and could even explain Phair's theory. If my cells are shutting down because of an over reaction to an infection, I'm going to be not producing enough of a whole host of bio chemicals essential for life function.

My back ground is in arboriculture and the Dutch Elm Disease (DED) was caused by a virulent fungus causing elm trees to overreact and cut the transportation of water up the tree in an attempt to stop the fungus getting to the whole tree, possibly a bit like Prusty is proposing, shut down the cells so the infection cant get in to them. DED did however kill millions of trees.

So how do we stop this response to danger? Remove the infectious agent, which is similar to what Learner did with long term anti viral regimes. Over time cells are reproduced virus free. I think it takes about 7 to 10 years to replenish all the cells in the body, hence long term application. But the medications are not really designed for this and as we know which infection is causing the overreaction anyway, and is it just one?

Another option is to stop the overreaction in the immune system. But, if we stop the immune system working whilst some of it needs to, many parts of it are essential to us for our existences.

Targeting the infectious agent with specifically designed drugs could be an answer, but I've read some of the infectious agents are now co evolving with us and could be part of an essential complex system and doing so could do more harm than good. Last year Ron Davis and OMF released an updated video saying something along the lines that they thought that a cheap treatment and one time application could be able to solve the ME/CFS problem, but after a short time the video disappeared with the unexplained theory, did anyone else see this? I think it could have been to target an infectious agent and remove it, but I'm just guessing.

The above is just what I've pieced together with my history of illness and symptoms, it may not be applicable to many sufferers, hopefully short time will tell. A guy called Dr Alex Shigo eventually explained how trees stop infection from moving through them and decaying them. Many people before he did it, where proposing what was happening with decay in trees, but he was the first to fully explain it and put the theory in the open, its called C.O.D.I.T. I'm hoping that the theory's we see for ME/CFS will lead very soon to someone doing something similar for our community.

 

[hunter1899]

I read these studies and it all just reads like things that won’t provide meaningful help or treatment until years from now. Then again I am new here and don’t have any real understanding of the science. Hopefully I’m wrong??

 

[Davsey27]

Tropics.Minimal emf

 

[keenly]

what is AM UV hormone building?

Light controls our biology. Not food, not the nuclear genome.

You build your hormones by LIGHT. Morning Red and UVA are essential. Few know. We are taught nothing about light, doctors are taught nothing about light.

Sunlight is not just about Hormone D, AKA Vitamin D. That is a tiny part.

 

[keenly]

For me Prusty's work and Naviaux theory of cell danger response aim to get to the root of the problem, are complementary and could even explain Phair's theory. If my cells are shutting down because of an over reaction to an infection, I'm going to be not producing enough of a whole host of bio chemicals essential for life function.

My back ground is in arboriculture and the Dutch Elm Disease (DED) was caused by a virulent fungus causing elm trees to overreact and cut the transportation of water up the tree in an attempt to stop the fungus getting to the whole tree, possibly a bit like Prusty is proposing, shut down the cells so the infection cant get in to them. DED did however kill millions of trees.

So how do we stop this response to danger? Remove the infectious agent, which is similar to what Learner did with long term anti viral regimes. Over time cells are reproduced virus free. I think it takes about 7 to 10 years to replenish all the cells in the body, hence long term application. But the medications are not really designed for this and as we know which infection is causing the overreaction anyway, and is it just one?

Another option is to stop the overreaction in the immune system. But, if we stop the immune system working whilst some of it needs to, many parts of it are essential to us for our existences.

Targeting the infectious agent with specifically designed drugs could be an answer, but I've read some of the infectious agents are now co evolving with us and could be part of an essential complex system and doing so could do more harm than good. Last year Ron Davis and OMF released an updated video saying something along the lines that they thought that a cheap treatment and one time application could be able to solve the ME/CFS problem, but after a short time the video disappeared with the unexplained theory, did anyone else see this? I think it could have been to target an infectious agent and remove it, but I'm just guessing.

The above is just what I've pieced together with my history of illness and symptoms, it may not be applicable to many sufferers, hopefully short time will tell. A guy called Dr Alex Shigo eventually explained how trees stop infection from moving through them and decaying them. Many people before he did it, where proposing what was happening with decay in trees, but he was the first to fully explain it and put the theory in the open, its called C.O.D.I.T. I'm hoping that the theory's we see for ME/CFS will lead very soon to someone doing something similar for our community.

Remove the infectious agent? Support redox and there is no need. Healthy redox and there are no infectious agents.

If your environment is destroying your mitochondria it does not matter what drugs or supplements you use, you will never get better.

Environment is everything. Your mitochondria determine your health, and our environemnt shapes our mitochondria.