Sing
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I have noticed only benefit from the 5 mg of hydrocortisone I take twice a day. This isn't enough to make me high at all and I haven't had those negative symptoms. I think everyone ought to at least understand that the hydrocortisone which is the same as cortisol which is what the adrenals make--is only ¼ of the strength of the same dosage of prednisone. Prednisone also apparently stays in the body longer. The hydrocortisone I take does help balance out my energy, lifting it enough during the day that I am functional.
Comparing different forms of this hormone drug can be apples to oranges. A physiological replacement dose I have heard might be at least 30 mg a day, maybe 40 of hydrocortisone. And as long as one has an adrenal gland still working, it is very important not to take this much as this will suppress the adrenals. However, some think--and it is my experience--that a low dose of the hydrocortisone/cortisol form, well below the physiolgical replacement dose, can help some people.
I understand my problem, at least hormonally, to be an underfunctioning HPA axis rather than a "tired" or sick or impaired adrenal gland. It just isn't being signalled enough to meet the normal needs of the body.
My aim is not to advertise and promote cortisol for ME/CFS, but to speak to the possibility that it can be useful in low enough doses for those who do not have sufficient circulating in their blood. However, as Dr. Edwards writes, perhaps this is mistaken or will eventually be so.
Comparing different forms of this hormone drug can be apples to oranges. A physiological replacement dose I have heard might be at least 30 mg a day, maybe 40 of hydrocortisone. And as long as one has an adrenal gland still working, it is very important not to take this much as this will suppress the adrenals. However, some think--and it is my experience--that a low dose of the hydrocortisone/cortisol form, well below the physiolgical replacement dose, can help some people.
I understand my problem, at least hormonally, to be an underfunctioning HPA axis rather than a "tired" or sick or impaired adrenal gland. It just isn't being signalled enough to meet the normal needs of the body.
My aim is not to advertise and promote cortisol for ME/CFS, but to speak to the possibility that it can be useful in low enough doses for those who do not have sufficient circulating in their blood. However, as Dr. Edwards writes, perhaps this is mistaken or will eventually be so.
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