I've done a bit of research, and it sounds like the issue is likely related to my adrenals. What tests would rule-in or rule-out this theory? 24-hour cortisol study? I have also read that in addition to cortisol issues, adrenaline surges and insulin spikes can cause a similar response. I had a cortisol study done a few years back - can't recall whether it was via blood or urine or other details - but the results suggested that my levels were inverted. I think my doctor recommended ashwaganda...in addition to a daily regimen of adrenal support supplements. I also have reactive hypoglycemia, so often have insatiable cravings. ME/CFS has greatly effected me cognitively, which has made treatment more difficult. I'm regrouping, with the mind-set that first increasing qualitative sleep, best I can, will help me to better understand ME/CFS and be a better patient. Anyone here take Seriphos? Not sure if I should sample or have the tests above first? TIA