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I'm trying to figure out if the cheaper Valganciclovir drug powder that I can put into capsules, provided the powder has enough flow, will have the exact same effect (absorption, bio-availability etc.) as the tablet formulation...
Excipients and the type of coating can affect absorption (enteric coating). But so far it seems like it will have the exact same effect after I looked at the excipients, which shouldn't in this case affect absorption, and found out that the tablets are film-coated.
This means that the tablets are for taste, ease of swallowing, and because they can be teratogenic. The ISMP Do Not Crush PDF seems to confirm this.
Excipients:
I don't know if this is the right place to ask about this, but can anyone provide input on this?
Excipients and the type of coating can affect absorption (enteric coating). But so far it seems like it will have the exact same effect after I looked at the excipients, which shouldn't in this case affect absorption, and found out that the tablets are film-coated.
This means that the tablets are for taste, ease of swallowing, and because they can be teratogenic. The ISMP Do Not Crush PDF seems to confirm this.
Excipients:
Tablet core:
Tablet film-coat:
- Povidone K30 [binder]
- Crospovidone [disintegrant]
- Microcrystalline cellulose [binder]
- Stearic acid [lubricant]
Opadry Pink 15B24005 containing:
- Hypromellose [coating agent]
- Titanium dioxide (E171) [pigment]
- Macrogol 400 [plasticizer]
- Red iron oxide (E172) [coloring agent]
- Polysorbate 80 [solubilizing agent]
I don't know if this is the right place to ask about this, but can anyone provide input on this?