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Vaccines and HIV info relate to xmrv?


Senior Member
So does anyone know the update on Edward Hooper and Tom Curtis brilliant exposes some years back about Koprowski's potentially bad vaccines for polio in the 60s and AIDS (and thus maybe ME, XMRV)????



1932: Young Albert B. Sabin identifies and isolates a monkey virus that has killed a polio researcher at Bellevue Hospital, in New York. It is later named monkey B virus.
1946: Hilary Koprowski and his superior at Lederle Laboratories, in Pearl River, New York, begin work on live polio-virus vaccine.
1950: Koprowski tests first polio vaccine on human beings - a live oral vaccine. The virus is grown in chicken eggs and passed through rat brains.
1954: Jonas Salk introduces his killed polio vaccine, made from virus grown in monkey kidneys.
1955: India, reacting to the widespread slaughter of monkeys to make vaccines, restricts exports of rhesus macaques.
1956: Sabin begins testing a live polio vaccine on humans.
1957: Koprowski's vaccine, now grown in as monkey kidneys, becomes the first oral polio vaccine to be tested on a large population - in the Belgian Congo. More than 240,000 are vaccinated in the first six weeks, most in the remote eastern part of the country.
1957: Sabin begins field trials of his vaccine in the Soviet Union. Later, upward of 70 million get it there.
1958: A three-year campaign to vaccinate African children in Leopoldville (now Kinshasa, Zaire) begins. Some 75,000 children receive Koprowski's vaccine.
1959: Nationalist riots erupt in Leopoldville.
1959: The first detection of HIV in Leopoldville, according to two standard blot tests of stored blood conducted in 1986.
1959: Sabin reports that an unidentified monkey virus contaminated Koprowski's Congo vaccine.
1960: Independence and civil war come to the Congo; Belgian workers depart. At least 325,000 Congolese, maybe many more, have been inoculated. No long-term follow-up is done.
1960: First case of HIV, according to a rough estimate based on genetic-sequencing calculations by Gerald Myers of Los Alamos National Laboratory, New Mexico.
1961: Batches of Salk and Sabin vaccine given to millions worldwide are reported to have been contaminated with SV40, a monkey virus that causes cancer in hamsters.
1961: French-speaking Haitians stream into the former Belgian Congo to take over jobs previously held by Belgian colonialists.
1961-62: Sabin vaccine is licensed in the U.S. and becomes vaccine of choice. Koprowski's is frozen out.
1962: Several more AIDS cases originate in Zaire in this year and later, according to subsequent testing. Some scientists believe that AIDS radiates outward in Africa from Zaire.
1967: Marburg monkey virus kills polio researchers in Germany and Yugoslavia.
1980: A new, fatal disease - later identified as AIDS - begins to appear among American homosexual men.
1982: An AIDS-like disease is identified as killing monkeys at California and Massachusetts primate centers; a virus is later isolated as the culprit. The contagions, it turns out, have been wiping out captive monkeys since 1969.
1983: AIDS virus isolated by Luc Montagnier in Paris.
1985: Researchers report finding HIV among remote villagers in the Kivu District, in eastern Zaire.
1987: "Missing link" chimps found with closest thing yet to the human AIDS virus.
1991: Some strains of simian immunodeficiency virus (SIV) are found to be almost identical to HIV-2, the form of AIDS plaguing West Africa. This boosts speculation that a monkey with a virus quite dose to HIV-1 eventually will be found.
1991 (December): Researcher Robert C. Bohannon requests samples of Koprowski's, Salk's and Sabin's seed stocks to check for contaminating monkey viruses. No response to date from Koprowski; limited success with the Food and Drug Administration. - T. C.


Senior Member
"Like Salk and Sabin, Koprowski had the best intentions: He wanted to eradicate a debilitating and deadly scourge. But with what we know now, it's clear there was a certain hubris involved in the rough-and-ready campaigns to conquer polio. There is evidence that all three pioneers used vaccines inadvertently contaminated with viruses from a species dangerously close to our own. If the Congo vaccine turns out not to be the way AIDS got started in people, it will be because medicine was lucky, not because it was infallible." TC