MEGA is Prof George Davey-Smith, University of Bristol; Prof Chris Ponting, University of Edinburgh; Prof Colin Smith, University of Brighton; Prof Caroline Relton, University of Bristol; Tony Bartlett, Somalogic; Dr Rick Dunn, University of Birmingham; Prof Julia Newton, University of Newcastle; Sonya Chowdhury, Action for M.E., representing the patient charity members of the UK CFS/M.E. Research Collaborative Board; Prof Andrew Morris, University of Edinburgh; Dr Simon Collin, University of Bristol; Prof David Ford, Swansea University; Dr Esther Crawley, University of Bristol; Prof Paul Moss, University of Birmingham; Prof Peter White, Queen Mary University London; Prof Jim Horne, Loughborough University; Prof Maria Fitzgerald, University College London; and Prof Paul Little, University of Southampton.