UK: Low-dose naltrexone as a treatment for chronic fatigue syndrome (2020)

[J.G]

I took LDN for ~15 months in doses gradually building up to 4.5mg/day. It sadly did absolutely nothing for me. N=1, obviously. I have textbook post-viral MECFS.

 

[Pyrrhus]

Related discussion:

Potential Therapeutic Benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of Transient Receptor Potential Melastatin 3 Ion Channels in Pathophysiology and Treatment (Cabanas et al., 2021)
https://forums.phoenixrising.me/threads/potential-therapeutic-benefit-of-low-dose-naltrexone.84779/

 

[Rufous McKinney]

I took LDN for ~15 months in doses gradually building up to 4.5mg/day. It sadly did absolutely nothing for me. N=1, obviously. I have textbook post-viral MECFS.

I am impressed that the study below: actually measured something, as opposed to just asking if you feel less tired.

I'm really tired of the subjectivity in so many of these studies about fatigue, PEM etc.

So they actually measured something. It would be interesting to me, to know if I had that issue but nobody measured anything, as usual.

 

[Wishful]

I'm really tired of the subjectivity in so many of these studies about fatigue, PEM etc.

ME research would be much easier, and potentially of much higher quality, if ME had something we could measure. There probably is something, but no one has figured it out yet.