I have seen DCA used for cancer in clinics I've been in, and I wouldn't use it without an expert doctor's supervision.Dichloroacetate sodium
Its safety, based on both non-clinical and clinical studies, is of significant concern. In non-clinical studies, dicholoroacetate shows potential toxicity in multiple organs as well as increased carcinogenicity. It also shows decreased fertility in rats. Toxicity was also noted in clinical studies, primarily involving the nervous sytem. Dichloroacetate also exhibits significant inter-individual variation in absorption and excretion, and the drug accumulates over time, complicating both dosing and the management of any toxic effects. FDA is aware of one study being closed due to safety concerns and patient deaths.
From the 2016 FDA compounding committee briefing document on DCA:
I have seen DCA used for cancer in clinics I've been in, and I wouldn't use it without an expert doctor's supervision.
The initial 10 patients were treated with a nutriceutical consisting of the 400 mg of sodium salt of dichloroacetate (DCA) plus 100 mg Vitamin B1. Afterwards the formulation was extended by adding alfa-lipoic acid (ALA), acetyl-l-carnitine and the oxidoreductase ubiquinone Q10.
Among the non-responders several organic diseases were detected, including among others, severe osteoporosis due to hyperparathyroidism, late onset hypogonadism (LOH), a neuro-endocrine tumour, early stage multiple sclerosis, and autoimmune limbic encephalitis. In these patients the ME/CFS complaints should be classified as secondary [2, explaining the lack of response to nutriceutical treatment.
I have seen it successfully used to beat cancer, so nothing killed those patents as they're still alive.Since it's used in cancer trials, we kind of need to know if it was the cancer that killed them or the DCA.
I have seen it successfully used to beat cancer, so nothing killed those patents as they're still alive.
There is also the experiment and info on pages 6-10 of the attached.